Use of MRS to Identify Chronic Injury Post-Stroke
This invention involves using magnetic resonance spectroscopy (MRS) to identify lipid-laden foam cells to diagnose a chronic stroke injury. This technology is specifically meant for monitoring patients post-stroke brain injury. This largely relates to improving management patient care and advancing stroke therapeutics.
Background:
Currently, MRS...
Published: 2/10/2025
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Inventor(s): Helena Morrison, Theodore Trouard
Keywords(s):
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Diagnostics
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Plasmid pNL4-3, HIV Clone For Easy Mutational Changes
Plasmid DNA (clone pNL4-3) that produces infectious HIV-1 virus particles in a wide variety of cells as described in the J Virol. 1986 Aug;59(2):284-91 and developed in the laboratory of Dr. Malcolm Martin at the National Institute of Allergy and Infectious Diseases.
Published: 10/28/2024
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Inventor(s): John Leonard, Malcolm Martin, Rosamond Rutledge-Burns, Theodore Theodore, Ronald Willey, Thomas Folks, Akio Adachi, Arnold Rabson
Keywords(s): 114, AIDS Research & Reference Reagent Program, CHANGES, CLONES, DDXXXX, DNA, EASY, HIV, INFECTIOUS, Listed LPM Ano as of 4/15/2015, MUTATIONAL, Novel, PLASMID, pNL4-3, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RM, VLXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease
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Phase Change Nanodroplet - Liposome Conjugates for Enhanced Drug Delivery
This technology utilizes phase-change nanodroplet-liposome conjugates to achieve targeted drug delivery of oncology therapeutics. The technology uses ultrasound to convert the nanodroplet into a gas, whereby this cavitation of the nanoparticles cases stress on the tight junction areas of the brain. The cavitation will temporarily make the blood-brain...
Published: 4/3/2023
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Inventor(s): Theodore Trouard, Terry Matsunaga, Marek Romanowski
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Materials > Nanomaterials, Technology Classifications > Healthcare Portfolios > Oncology
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Radial Fast Spin-Echo (FSE) MRI Pulse Sequence
This invention is a software method that combines radial imaging (taking MRI data radially--from the center, out) with fast spin-echo (FSE) imaging to create faster, more accurate images.
This technology has been demonstrated to effectively image human brains, abdominal regions, and livers.
Background:
Magnetic Resonance Imaging (MRI) is a very useful...
Published: 4/3/2023
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Inventor(s): Maria Altbach, Theodore Trouard, Arthur Gmitro
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging
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