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Search Results - technology+classifications+%3e+research+tools+%3e+therapeutics
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Magnetically Templated Tissue Engineering Scaffolds
Repairs Peripheral Nerve Injuries by Magnetically Guiding the Construction of Bioscaffolds These magnetically templated tissue engineering scaffolds for biomedical applications, particularly as nerve guides for peripheral nerve injury repair. Peripheral nerve injuries (PNI) have a significant socioeconomic impact, resulting in over 8 million restricted...
Published: 3/28/2023
|
Inventor(s):
Carlos Rinaldi
,
Andrew Garcia
,
Zin Khaing
,
Christopher Lacko
,
Christine Schmidt
Keywords(s):
Category(s):
Technology Classifications > Medical Devices > Consumable
,
Technology Classifications > Research Tools > Therapeutics
Galectin Candidate Therapeutic for Modulating Immune Response
Regulates Inflammation and Immune Responses at Lower Doses Than Other Galectin Therapeutics This fusion protein is composed of galectin-1 and galectin-3 and is a candidate therapeutic for modulating immune responses and treating inflammation. The global autoimmune disease therapeutics market should reach $1.5 billion by 2025. Galectins are promising...
Published: 12/9/2021
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Inventor(s):
Gregory Hudalla
,
Margaret Fettis
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Therapeutics
Multicellular Living Drug Platform for Targeted Treatment of Various Diseases
Isolated Micro-Ecosystems Secrete Drug Molecules at Controlled Doses and Locations This drug platform employs living multicellular assemblies that can deliver drug molecules in controlled patterns to specific tissues in order to perform complex therapeutic functions. Unlike standard small-molecule drugs and biopharmaceuticals, living drugs are therapeutic...
Published: 11/18/2021
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Inventor(s):
Yunwei Cao
,
Tianyuan Xiao
,
Shouguang Jin
,
Yousong Ding
Keywords(s):
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Research Tools > Therapeutics
Electroactive Biodegradable Polymers for Targeted Drug Therapy
Controlled Administration and Complete Polymer Breakdown Allows for Enhanced Delivery and Nontoxic Implementation Biodegradable supramolecular polymers that receive and transmit electrochemical information may be employed for efficient and effective medicinal treatment. Targeted drug delivery (occasionally employing stimuli-responsive materials) has...
Published: 6/27/2021
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Inventor(s):
John Hardy
,
Christine Schmidt
Keywords(s):
biocompatible drug delivery
,
biodegradable drug delivery
,
Biomaterials
,
conducting polymers
,
Drug Delivery (controlled)
,
time-released drug delivery
Category(s):
Technology Classifications > Human Health Care > Drug Delivery
,
Technology Classifications > Medical Devices > Consumable
,
Technology Classifications > Research Tools > Therapeutics
Purification of AAV Serotypes Using Off-the-Shelf Reagents
Purification Protocol Is Easily Adaptable to Large-Scale Manufacturing of Versatile, Successful Gene Therapy Delivery VehiclesThis purification of recombinant adeno-associated virus serotype three (rAAV3), eight (rAAV8) and nine (rAAV9) uses inexpensive, efficient reagents and is easily adaptable to large-scale manufacturing. An AAV is a small nonenveloped...
Published: 6/27/2021
|
Inventor(s):
Barry Byrne
,
Mark Potter
Keywords(s):
Gene Therapy
,
Purification
,
rAAV
,
Serotype nine
Category(s):
Technology Classifications > Human Health Care > Gene Therapy
,
Technology Classifications > Research Tools > Therapeutics
Magnetic Remote Targeting System for Controlling the Activity of Growth Factors
Provides Control of the Distribution and Activity of Growth Factors Used in Tissue Regeneration These magnetic nanoparticles conjugated with transforming growth factor beta (TGF-ß) and its latent complex accurately target delivery to specific locations and remotely activate or deactivate the growth factor, greatly augmenting the potential of TGF-ß...
Published: 6/27/2021
|
Inventor(s):
Jon Dobson
,
Adam Monsalve
Keywords(s):
Biomedical Engineering
,
Growth factors
,
magnetic
,
Nanoparticles
,
regenerative medicine
,
Tissue Engineering
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
Receptor-Ligand Combination for Specific Drug Delivery to the Brain
Molecule Crosses the Blood-Cerebrospinal Fluid Barrier to Deliver Therapy into Targeted CellsThis engineered receptor-ligand combination targets and crosses the brain barriers of mammals to deliver drugs and therapeutics to the brain. About 12 percent of all deaths worldwide are caused by neurological disorders such as Alzheimer’s, Parkinson’s...
Published: 12/20/2021
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Inventor(s):
Hector Mendez-Gomez
,
Nicholas Muzyczka
Keywords(s):
Blood-brain barrier
,
brain delivery
,
brain-specific drug delivery
,
Gene Therapy
,
receptor-mediated transcytosis
Category(s):
Technology Classifications > Human Health Care > Drug Delivery
,
Technology Classifications > Human Health Care > Gene Therapy
,
Technology Classifications > Research Tools > Therapeutics
Small Peptide Expression System in Mammalian Cells
Treats Various Diseases Including Cancer, Neurodegenerative Disorders and DiabetesThis small peptide expression technique effectively expresses small peptides through gene delivery in mammalian cells providing promising targets for therapeutic interventions for many pathological conditions. The use of peptides as mainstream drug candidates has been...
Published: 6/27/2021
|
Inventor(s):
William Hauswirth
,
Alfred Lewin
,
Qiuhong Li
Keywords(s):
Cell penetrating peptide
,
expression vector
,
furin cleavage
,
Plasmid
,
rAAV
,
small peptide
Category(s):
Technology Classifications > Research Tools > Therapeutics
Polyclonal Antibody to DNA Methyltransferase (DNMT1)
Targeting a Protein That Methylates DNA Scientists at the University of Florida have developed a wide variety of monoclonal and polyclonal antibodies, cell lines, vectors and biological materials that can be used in other research projects. Anyone interested in accessing these materials via a license from the University of Florida should contact our...
Published: 6/27/2021
|
Inventor(s):
Keith Robertson
Keywords(s):
Antibody
,
Chromatin
,
DNA Methylation
,
DNMT1
,
Gene Regulation
,
Immunoprecipitation
,
Western Blotting
Category(s):
Technology Classifications > Research Tools > Biological Materials
,
Technology Classifications > Research Tools > Diagnostics
,
Technology Classifications > Research Tools > Therapeutics