Inteum Company
Links
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - technology+classifications+%3e+research+tools+%3e+therapeutics
12
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
SPLICER: Small Molecule-Inducible Gene Expression Switches
Enables Ligand-Inducible Regulation of Gene Expression or Knockdown This small molecule-inducible gene expression based on riboswitches (SPLICER) enables precise, drug-responsive control of gene expression for safer and more flexible gene and cell therapies. In mammalian cells, alternative splicing greatly expands the diversity of RNA sequences. These...
Published: 9/2/2025
|
Inventor(s):
Eric Wang
,
Yu Zhou
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
Autoregulated MBNL Gene Therapy for Myotonic Dystrophy
Next-Generation Gene Therapy Vectors with Tunable, Tissue-Specific, and Auto-Regulated Expression for Superior Safety and Efficacy This technology introduces recombinant adeno-associated virus (rAAV) vectors engineered to enable precise, regulated expression of therapeutic genes. Recombinant viruses can deliver therapeutic gene expression constructs...
Published: 9/2/2025
|
Inventor(s):
Eric Wang
,
Andy Berglund
,
Elizabeth Delgado
,
Jana Jenquin
,
Derek Muscato
,
Ona McConnell
,
Leanne Adams
,
Maria Valero Quiros
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
Alternative Splicing Cassettes for AAV Gene Therapy Regulation
Uses Tissue-Specific Exons for Precise Control Therapeutic Cargo Delivery These alternative splicing cassettes use tissue specific exons to precisely deliver adeno-associated virus (AAV) cargo. AAVs are a commonly used gene therapy vector for delivering genetic material into cells. Current technology relies upon tissue specific promoters to guide and...
Published: 9/9/2025
|
Inventor(s):
Eric Wang
,
Keril Poukalov
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
Magnetically Templated Tissue Engineering Scaffolds
Repairs Peripheral Nerve Injuries by Magnetically Guiding the Construction of Bioscaffolds These magnetically templated tissue engineering scaffolds for biomedical applications, particularly as nerve guides for peripheral nerve injury repair. Peripheral nerve injuries (PNI) have a significant socioeconomic impact, resulting in over 8 million restricted...
Published: 3/28/2023
|
Inventor(s):
Carlos Rinaldi
,
Andrew Garcia
,
Zin Khaing
,
Christopher Lacko
,
Christine Schmidt
Keywords(s):
Category(s):
Technology Classifications > Medical Devices > Consumable
,
Technology Classifications > Research Tools > Therapeutics
Galectin Candidate Therapeutic for Modulating Immune Response
Regulates Inflammation and Immune Responses at Lower Doses Than Other Galectin Therapeutics This fusion protein is composed of galectin-1 and galectin-3 and is a candidate therapeutic for modulating immune responses and treating inflammation. The global autoimmune disease therapeutics market should reach $1.5 billion by 2025. Galectins are promising...
Published: 12/9/2021
|
Inventor(s):
Gregory Hudalla
,
Margaret Fettis
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Therapeutics
Multicellular Living Drug Platform for Targeted Treatment of Various Diseases
Isolated Micro-Ecosystems Secrete Drug Molecules at Controlled Doses and Locations This drug platform employs living multicellular assemblies that can deliver drug molecules in controlled patterns to specific tissues in order to perform complex therapeutic functions. Unlike standard small-molecule drugs and biopharmaceuticals, living drugs are therapeutic...
Published: 11/18/2021
|
Inventor(s):
Yunwei Cao
,
Tianyuan Xiao
,
Shouguang Jin
,
Yousong Ding
Keywords(s):
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Research Tools > Therapeutics
Electroactive Biodegradable Polymers for Targeted Drug Therapy
Controlled Administration and Complete Polymer Breakdown Allows for Enhanced Delivery and Nontoxic Implementation Biodegradable supramolecular polymers that receive and transmit electrochemical information may be employed for efficient and effective medicinal treatment. Targeted drug delivery (occasionally employing stimuli-responsive materials) has...
Published: 6/27/2021
|
Inventor(s):
John Hardy
,
Christine Schmidt
Keywords(s):
biocompatible drug delivery
,
biodegradable drug delivery
,
Biomaterials
,
conducting polymers
,
Drug Delivery (controlled)
,
time-released drug delivery
Category(s):
Technology Classifications > Human Health Care > Drug Delivery
,
Technology Classifications > Medical Devices > Consumable
,
Technology Classifications > Research Tools > Therapeutics
Purification of AAV Serotypes Using Off-the-Shelf Reagents
Purification Protocol Is Easily Adaptable to Large-Scale Manufacturing of Versatile, Successful Gene Therapy Delivery VehiclesThis purification of recombinant adeno-associated virus serotype three (rAAV3), eight (rAAV8) and nine (rAAV9) uses inexpensive, efficient reagents and is easily adaptable to large-scale manufacturing. An AAV is a small nonenveloped...
Published: 6/27/2021
|
Inventor(s):
Barry Byrne
,
Mark Potter
Keywords(s):
Gene Therapy
,
Purification
,
rAAV
,
Serotype nine
Category(s):
Technology Classifications > Human Health Care > Gene Therapy
,
Technology Classifications > Research Tools > Therapeutics
Magnetic Remote Targeting System for Controlling the Activity of Growth Factors
Provides Control of the Distribution and Activity of Growth Factors Used in Tissue Regeneration These magnetic nanoparticles conjugated with transforming growth factor beta (TGF-ß) and its latent complex accurately target delivery to specific locations and remotely activate or deactivate the growth factor, greatly augmenting the potential of TGF-ß...
Published: 6/27/2021
|
Inventor(s):
Jon Dobson
,
Adam Monsalve
Keywords(s):
Biomedical Engineering
,
Growth factors
,
magnetic
,
Nanoparticles
,
regenerative medicine
,
Tissue Engineering
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
Receptor-Ligand Combination for Specific Drug Delivery to the Brain
Molecule Crosses the Blood-Cerebrospinal Fluid Barrier to Deliver Therapy into Targeted CellsThis engineered receptor-ligand combination targets and crosses the brain barriers of mammals to deliver drugs and therapeutics to the brain. About 12 percent of all deaths worldwide are caused by neurological disorders such as Alzheimer’s, Parkinson’s...
Published: 12/20/2021
|
Inventor(s):
Hector Mendez-Gomez
,
Nicholas Muzyczka
Keywords(s):
Blood-brain barrier
,
brain delivery
,
brain-specific drug delivery
,
Gene Therapy
,
receptor-mediated transcytosis
Category(s):
Technology Classifications > Human Health Care > Drug Delivery
,
Technology Classifications > Human Health Care > Gene Therapy
,
Technology Classifications > Research Tools > Therapeutics
1
2