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Search Results - margaret+fettis
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Galectin Candidate Therapeutic for Modulating Immune Response
Regulates Inflammation and Immune Responses at Lower Doses Than Other Galectin Therapeutics This fusion protein is composed of galectin-1 and galectin-3 and is a candidate therapeutic for modulating immune responses and treating inflammation. The global autoimmune disease therapeutics market should reach $1.5 billion by 2025. Galectins are promising...
Published: 1/20/2026
|
Inventor(s):
Gregory Hudalla
,
Margaret Fettis
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Therapeutics
More Stable and Potent Galectin-1 Homodimer for Therapeutic Use in Inflammatory Diseases
Potently Modulates the Immune Response in Autoimmune and Chronic Inflammatory Disease Conditions This polymer crosslinked, more stable Galectin-1 homodimer suppresses inflammation more potently than unmodified recombinant Galectin-1. Galectin-1 (Gal1) modulates innate and adaptive immunity by regulating dendritic cell migration, inducing activated...
Published: 1/20/2026
|
Inventor(s):
Margaret Fettis
,
Gregory Hudalla
Keywords(s):
galectin
,
immune modulation
,
Immunotherapy
,
Inflammation Reduction
,
Lymphocytes
,
Oxydation
,
Pegylation
,
Protein Therapy
Category(s):
Technology Classifications > Engineering > Materials
,
Technology Classifications > Human Health Care > Drug Delivery
,
Technology Classifications > Human Health Care > Therapeutics
Anchored Enzymes to Treat Inflammatory Diseases
Prolongs Residence of Immunosuppressive Enzymes at Sites of Inflammation Via Minimally-Invasive Injection This bifunctional fusion protein resets the immune system to promote healthy tissue function by anchoring enzymes to the site of inflammation. Biologic drugs used to treat inflammatory diseases are a market that exceeds $30 billion annually. Available...
Published: 1/20/2026
|
Inventor(s):
Benjamin Keselowsky
,
Gregory Hudalla
,
Evelyn Bracho-Sanchez
,
Shaheen Farhadi
,
Margaret Fettis
,
Sabrina Freeman
,
Antonietta Restuccia
Keywords(s):
Category(s):
Technology Classifications > Engineering > Materials
,
Technology Classifications > Human Health Care > Diagnostics
,
Technology Classifications > Human Health Care > Therapeutics