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Customizable Collagen-Mimetic Hydrogels for Precision Modeling and Bioscaffold Engineering

Synthesis of cysteine flanked collagen-mimetic peptides (CMPs) Invention Summary: Hydrogels are essential tools which can mimic extracellular matrix environments; however, current systems lack precise molecular-level control over crosslinking density and porosity. Conventional approaches utilize non-specific, generic biopolymers with statistical...

Published: 12/9/2025 | Inventor(s): Sonal Gahlawat, David Shreiber

Keywords(s): Bioengineering scaffolds, Biomaterials, Peptides

Category(s): Technology Classifications > Biomaterials, Technology Classifications > Physical Sciences & Engineering

Aerodynamic and vibration damping skin for cylindrical structures

Unit cell of locally-resonant lattice tuned to damp noise source. Invention Summary: During rocket launches and stage separations, intense vibrations and shock waves can damage sensitive payload electronics. Traditional isolation systems are often heavy and increase fuel consumption, making lightweight vibration-damping solutions essential....

Published: 12/2/2025 | Inventor(s): Jonathan Singer, Andrew Norris, Catherine Nachtigal, Bryan Llumiquinga, Matthew Kelsten, Paul Hoffecker

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Category(s): Technology Classifications > Physical Sciences & Engineering

Method to Achieve Total Acoustic Transmission between Water and Air

A plane wave is incident from the water side of the asymmetric panel. The plates are separated by ribs set a distance 𝑑 apart with the intermediate space assumed to be air. Invention Summary: Effective sound transmission between water and air is challenging due to the vastly different acoustic impedances. Current methods are limited as they...

Published: 11/20/2025 | Inventor(s): Andrew Norris, Hesam Bakhtiary Yekta

Keywords(s):

Category(s): Technology Classifications > Physical Sciences & Engineering

Scalable Magneto-Optical Trap and Gravimeter

(a) Side-view schematic of dual-MOT. (b) Mounted mirrors. (c) MOT mirror. (d) Incident laser beam. (e) Passing through laser beam after the 1st mirror. (f) Passing-through laser beam after the 2nd mirror. Invention Summary: Cold-atom-sensors such as atomic gravimeters have been used in geological surveys and navigation. The complexities involved...

Published: 10/31/2025 | Inventor(s): Xuejian Wu, Timothy Nguyen, Mariam Mchedlidze

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Category(s): Technology Classifications > Sensors, Technology Classifications > Physical Sciences & Engineering

Scalable Magneto-Optical Trap and Gravimeter

Published: 10/31/2025 | Inventor(s): Xuejian Wu, Timothy Nguyen, Mariam Mchedlidze, Guanghui Su

Keywords(s): Machines & Instruments

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors

Plasma-Electrochemical System for Green Ammonia Production

Invention Summary: Ammonia is one of the most widely produced industrial chemicals, primarily used for fertilizer production. Ammonia has also emerged as a potential hydrogen carrier for green power storage. The dominant industrial process for ammonia production is the Haber-Bosch process, which operates under high temperature and high pressure...

Published: 10/27/2025 | Inventor(s): Huixin He, Yiguang Ju, Zhiyuan Zhang

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Category(s): Technology Classifications > Catalysts, Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering

Atomic Scale Topological Magneto-resistance Sensor

Experimental setup for electrical transport measurement on the pyrochlore heterostructure, and STM image near the interface of EIO/DTO. Invention Summary: In advanced electronics and quantum technologies, there is a growing demand for materials that offer highly tunable, low-power, and robust quantum states for applications such as magnetic...

Published: 10/29/2025 | Inventor(s): Jedediah Pixley, Tsung-Chi Wu, Yueqing Chang, Jak Chakhalian, Mikhail Kareev

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Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors, Technology Classifications > Nanotechnology, Technology Classifications > Electronics/Semiconductor

Nanoscale 3D Thermal Metrology via Scanning Electron Resistance Thermometry (SE-TherM)

(A) SEM image and (B) Temperature map of the device under test Invention Summary: It can be difficult to measure thermal properties at the nanoscale on operating microelectronics in a nondestructive, non-contact and real-time manner. The lack of such nanoscale thermal metrology tools affects quality control in modern microelectronics and...

Published: 10/30/2025 | Inventor(s): Amin Reihani

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Category(s): Technology Classifications > Electronics/Semiconductor, Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Research Tools, Technology Classifications > Sensors

Biomaterial-mediated Extracellular Vesicle Delivery CNS Regeneration

Reduction in cortical lesion volume post-TBI (a) and post-treatment (b); remyelination as shown by luxol fast blue-staining post-TBI (c) and post-treatment (d); and enhanced expression of occludin post treatment (f) as compared to post-TBI (e). Invention Summary: More than 3 billion people worldwide are affected by central nervous system...

Published: 10/3/2025 | Inventor(s): Joshua Stein, Ki-Bum Lee, Inbo Han

Keywords(s): Bioengineering scaffolds, Biomaterials, Drug Delivery, Spinal Cord

Category(s): Technology Classifications > Biomaterials, Technology Classifications > Physical Sciences & Engineering

Gold Nanocluster-Based PROTAC Targeting pTau

Gold nanocluster binds both pTau and E3 ligase, initiating the ubiquitin-proteasome pathway and degrading pTau, as seen via immunostaining (Blue – Hoechst, red – TUJ1, green – pTau) Invention Summary: Hyperphosphorylated tau protein, a key clinical marker for various neurodegenerative diseases, leads to abnormal aggregation...

Published: 9/12/2025 | Inventor(s): Sarah Nevins, Ki-Bum Lee

Keywords(s): Alzheimer’s, Drug Delivery, Inflammation, Nanoparticles

Category(s): Technology Classifications > Biomaterials, Technology Classifications > CNS Disorder, Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering

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