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Small Molecule mGlur5 Agonists for Remyelination in Multiple Sclerosis
​ Invention Summary: Multiple sclerosis (MS) is a debilitating autoimmune condition caused by an overactive immune system that destroys the myelin surrounding nerves cells. Symptoms of MS include pain, impaired coordination, vision loss, and overall weakness. Current treatment options work to suppress the immune system to slow progression of...
Published: 6/5/2026   |   Updated: 6/5/2026   |   Inventor(s): Hiroko Nobuta, Jacques Roberge, Cheryl Dreyfus, Yangyang Huang, Pingyue Pan
Keywords(s):  
Category(s): Technology Classifications > CNS Disorder, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
RNA-Aptamer-Mediated CRISPR Base Editing Platform for Agriculture License
​ Description of the base editing (BE) platform and proof of principle in prokaryotic. (A) Components of the platform. (B) Schematic of the modular complex at the target sequence. Collantes, J C et al. The CRISPR journal (2021). Invention Summary: The CRISPR/Cas system has become a foundational technology for precision genome engineering...
Published: 6/5/2026   |   Updated: 6/5/2026   |   Inventor(s): Shengkan (Victor) Jin, Juan-Carlos Collantes
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Research Tools, Technology Classifications > Therapeutics, Technology Classifications > Gene Therapy
Programmable RNA Lattice Platform for Intracellular Molecular Display and Assembly
​ Representative co-transactionally folded RNA lattices displaying light-up aptamers (green) in living cells. Invention Summary: The ability to design and arrange functional RNA elements in defined intracellular architectures is increasingly important for target validation, assay development, synthetic biology, and therapeutic discovery. Current...
Published: 6/2/2026   |   Updated: 6/1/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences
Negative Pressure-Assisted DNA Delivery
​ Fig.1. Dermal suction induces long-lasting antigen expression and T-cell response. (A) Dermal suction via a small hand-held device with a 6-mm orifice against the skin. Inset: immune response is 100 times stronger when compared with injection alone. (B) Post-suction skin demonstrates no damage nor erythema. (C) and (D): Benchmarking of suction against...
Published: 5/15/2026   |   Updated: 5/15/2026   |   Inventor(s): Hao Lin, Jonathan Singer, David Shreiber, Jerry Shan, Jeffrey Zahn, Emran Lallow, Juliet Melnik, Nandita Jhumur
Keywords(s): Drug Delivery
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Vaccine
Delivery of exogenous protein/peptide cargoes to the cell cytosol
​ Survival curves of weanling mice immunized with LFn-LACV-Gc or LFn-LACV-N compared with LFn-ZIKV-NS3 and subsequently challenged with LACV Invention Summary: Novel T cell-based vaccine was developed by utilizing a fusion protein by binding a target protein or peptide molecule with transport factor derived from Bacteria. The target protein...
Published: 5/12/2026   |   Updated: 5/12/2026   |   Inventor(s): Bobby Brooke Herrera
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease, Technology Classifications > Vaccine
T cell-based vaccines
​ Survival curves of weanling mice immunized with LFn-LACV-Gc or LFn-LACV-N compared with LFn-ZIKV-NS3 and subsequently challenged with LACV Invention Summary: Novel T cell-based vaccine was developed by utilizing a fusion protein by binding a target protein or peptide molecule with transport factor derived from Bacteria. The target protein...
Published: 5/12/2026   |   Updated: 5/12/2026   |   Inventor(s): Bobby Brooke Herrera
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Vaccine
AmpliFAST - PCR in the Palm of Your Hand
​ AmpliFast technology for in home diagnostics. Cassette driven diagnostic kit for fast and early detection of infectious diseases. Invention Summary: There is a need to develop easy-to-use diagnostic kits based on newly discovered enzymes that enable nucleic acid amplification. Rutgers researchers have developed a new technology that...
Published: 5/12/2026   |   Updated: 5/12/2026   |   Inventor(s): Bobby Brooke Herrera
Keywords(s):  
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > COVID-19, Technology Classifications > Research Tools
Programmable intracellular RNA scaffolds for integrating sensing and regulation
​ Co-transactionally folded RNA nanostructures in living cells. Invention Summary: Biomarker validation and intracellular RNA detection require tools that are precise, scalable, and capable of capturing complex gene expression patterns. Current approaches, including CRISPR-based systems, RNA interference, and RNA sponge technologies, are often...
Published: 6/1/2026   |   Updated: 5/1/2026   |   Inventor(s): Fei Zhang, Xu (leo) Chang, Jean-Pierre Etchegaray, Maciej Jeziorek
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences
Monoclonal, Inducible, and Traceable Mesenchymal Stem Cell Platform for Cell Therapy
​ This figure illustrates the engineered Mesenchymal Stem Cells are monoclonal, conditionally immortalized (inducible), non-tumorigenic, and traceable in vitro and in vivo (bioluminescent imaging). The engineered MSCs have maintained their multipotency and chemotaxis capability (tumor targeting). The developed MSC platform is capable of delivering...
Published: 5/15/2026   |   Updated: 5/1/2026   |   Inventor(s): Arash Hatefi, Mohammad Massumi
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences
Antiviral Compositions for Enterovirus D68 and an FP-Based Method for Validating Candidate Compounds
​ Invention Portfolio Summary: Enterovirus D68 (EV-D68) is an RNA virus in the Picornaviridae family, is a re-emerging pediatric pathogen associated with recurrent outbreaks, can cause severe respiratory disease, and has also been linked to acute flaccid myelitis (AFM), whose incidence has risen steadily over the past decade. There are no approved...
Published: 3/27/2026   |   Updated: 3/27/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences
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