Search Results - technology+classifications+%3e+biomaterials

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Customizable Collagen-Mimetic Hydrogels for Precision Modeling and Bioscaffold Engineering
​ Synthesis of cysteine flanked collagen-mimetic peptides (CMPs) Invention Summary: Hydrogels are essential tools which can mimic extracellular matrix environments; however, current systems lack precise molecular-level control over crosslinking density and porosity. Conventional approaches utilize non-specific, generic biopolymers with statistical...
Published: 12/9/2025   |   Inventor(s): Sonal Gahlawat, David Shreiber
Keywords(s): Bioengineering scaffolds, Biomaterials, Peptides
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Physical Sciences & Engineering
Biomaterial-mediated Extracellular Vesicle Delivery CNS Regeneration
​ Reduction in cortical lesion volume post-TBI (a) and post-treatment (b); remyelination as shown by luxol fast blue-staining post-TBI (c) and post-treatment (d); and enhanced expression of occludin post treatment (f) as compared to post-TBI (e). Invention Summary: More than 3 billion people worldwide are affected by central nervous system...
Published: 10/3/2025   |   Inventor(s): Joshua Stein, Ki-Bum Lee, Inbo Han
Keywords(s): Bioengineering scaffolds, Biomaterials, Drug Delivery, Spinal Cord
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Physical Sciences & Engineering
Gold Nanocluster-Based PROTAC Targeting pTau
​ Gold nanocluster binds both pTau and E3 ligase, initiating the ubiquitin-proteasome pathway and degrading pTau, as seen via immunostaining (Blue – Hoechst, red – TUJ1, green – pTau) Invention Summary: Hyperphosphorylated tau protein, a key clinical marker for various neurodegenerative diseases, leads to abnormal aggregation...
Published: 9/12/2025   |   Inventor(s): Sarah Nevins, Ki-Bum Lee
Keywords(s): Alzheimer’s, Drug Delivery, Inflammation, Nanoparticles
Category(s): Technology Classifications > Biomaterials, Technology Classifications > CNS Disorder, Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering
Intervertebral Disc Repair Using a 3D Porous Hybrid Protein Nanoscaffold
​ Histological analysis of rat intervertebral disc tissue prior to (left) and post injury (center) compared to 6 weeks post treatment (right). Invention Summary: Degeneration of fibrocartilaginous tissues, such as intervertebral discs (IVD), knee menisci, and other tendon-bone junctions, can lead to debilitating pain. IVD degeneration is the...
Published: 8/12/2025   |   Inventor(s): Ki-Bum Lee, Letao Yang, Inbo Han
Keywords(s):  
Category(s): Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Biomaterials
Novel Sargassum-Based Polymer Composite Filaments for 3D Printing
​ Examples of prints made with Sargassum-loaded filament ​ Invention Summary: As a direct effect of ocean warming and nutrient enrichment, tons of brown macroalgae known as sargassum, have been accumulating on shores throughout...
Published: 12/9/2024   |   Inventor(s): David Salas-De La Cruz, Omar Movil-Cabrera
Keywords(s):  
Category(s): Technology Classifications > Ag Biotech, Technology Classifications > Agriculture, Technology Classifications > Biomaterials, Technology Classifications > Consumer & Household Goods, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials
Flexible Electronics and Sensors from Ion-Containing Polysaccharides
Top - The initial shape-fixing ratio of the cellulose polymer. Bottom- The shape-recovery ratio of the cellulose polymer after one week at room temperature. Invention Summary: Sustainable materials have become attractive to reduce carbon footprint. Cellulose is a biobased material that is renewable and economical. Recent discoveries...
Published: 7/9/2025   |   Inventor(s): David Salas-De La Cruz, Kevin Miller
Keywords(s):  
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Electronics/Semiconductor, Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors
Enhanced Intervertebral Disc Repair and Regeneration Using a Nano-Hybrid Gel
​ Nanomaterial (2D-Mn02)-embedded peptide hydrogel (NEPH) promotes cellular proliferation and tissue regeneration. Invention Summary: The limited capacity for regeneration, the presence of pro-inflammatory factors, and the complex extracellular matrix (ECM) microenvironment of degenerated intervertebral discs (IVD) remain significant issues...
Published: 12/3/2025   |   Inventor(s): Ki-Bum Lee, Brian Conley, Inbo Han
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices, Technology Classifications > Biomaterials, Technology Classifications > Physical Sciences & Engineering
Repurposing Anthelmintics: Effects of Rafoxanide and Copper-Functionalized SBA-15 Carriers Against Methicillin-Resistant Staphylococcus aureus
e: table;telerik-style-name: TableNormal;border-collapse: collapse; } Invention Summary: Due to the rise in bacterial resistance to conventional antibiotics, materials that can administer antimicrobial drugs in a regulated manner more effectively are critically needed. While new antibiotic classes are created and widely used, existing,...
Published: 8/12/2025   |   Inventor(s): Maricely Ramírez-Hernández, Javiera Norambuena-Morales, Tewodros Asefa, Jeffrey Boyd
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Animal Health & Care, Technology Classifications > Biomaterials, Technology Classifications > Nanotechnology
New method for biosynthesis of hydroxylated polymethoxyflavones
­ ​ The potential benefits of hydroxylated polymethoxyflavones Invention Summary: Hydroxylated polymethoxyflavones (OH-PMFs), are a class of novel flavonoid compounds found in citrus plants with very low abundance. OH-PMFs could be produced through semi-chemical or semi-bio synthesis from their PMF counterparts, but the technique to...
Published: 9/13/2024   |   Inventor(s): Qingrong Huang, Chi-Tang Ho, Shiwei Su
Keywords(s): Food preservatives/additives, Personal Care, Cosmeceuticals
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Physical Sciences & Engineering
Novel ChABC formulation with machine learning-guided automation
​ ​ Invention Summary: Spinal cord injury (SCI) leads to the formation of scar tissue. The scarring leads to the toughening of the extracellular matrix, or the cellular environment. One of the major concerns of SCI is the prevention of neuronal connection recovery, which can lead to paralysis or reduced control of the nervous system. For...
Published: 8/12/2025   |   Inventor(s): Adam Gormley, Matthew Tamasi, Shashank Kosuri, Michael Webb, Carlos Borca, Roshan Patel
Keywords(s): Biomaterials, Polymers & Composites, Proteins, Spinal Cord
Category(s): Technology Classifications > Biomaterials, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Software & Algorithms, Technology Classifications > Therapeutics
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