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Search Results - sergei+reverdatto
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Raman Spectroscopy for Probing Encapsulation of mRNA in Lipid Nanoparticles
This technology uses deep ultraviolet Raman spectroscopy and advanced data analysis to quickly and non-destructively measure how much mRNA is unencapsulated in lipid nanoparticles, improving quality control for mRNA vaccines and therapeutics without chemical labels. Background: Messenger RNA (mRNA) therapeutics, particularly those delivered via lipid...
Published: 6/12/2026
|
Updated: 6/11/2026
|
Inventor(s):
Igor Lednev
,
Alexander Shekhtman
,
Sergei Reverdatto
,
Sila Jin
,
Young Mee Jung
Keywords(s):
mRNA
,
Raman spectroscopy
,
spectroscopy
,
statistical analysis
,
Technologies
,
therapeutics
,
vaccines
Category(s):
Campus > University at Albany
,
Technology Classifications > Gene Therapy
Raman Spectroscopy for Testing Stability of RNA-based Vaccines and Drugs
A fast, less expensive, and more reliable method for assessing mRNA degradation in vaccines, that can also be used as a tool for the development of new RNA-based therapeutics. Background: The development of mRNA-based vaccines for COVID-19 offers the potential for a new medical paradigm based on RNA technology. Unfortunately, these drugs require...
Published: 1/29/2026
|
Updated: 10/24/2025
|
Inventor(s):
Igor Lednev
,
Alexander Shekhtman
,
Lamyaa Almehmadi
,
Sergei Reverdatto
Keywords(s):
drug stability
,
mRNA
,
mRNA stability
,
Raman spectroscopy
,
RNA
,
Technologies
,
vaccine stability
,
vaccines
Category(s):
Campus > University at Albany
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Therapeutics and Vaccines