Search Results - sameer+sonkusale

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A Digital-to-Analog Converter based on Resistive Interpolation Load Prof. Sameer Sonkusale at the Electrical and Computer Engineering Department at Tufts has developed a single chip integrated DAC using resistive interpolation (RIDAC) at the output branch of a multi-input operational amplifier. Digital-to-analog conversion is a key element in driving...

Published: 6/10/2022 | Inventor(s): Sameer Sonkusale, Wei Wang

Keywords(s):

Category(s): Device, Semiconductor

Immunotherapy That Converts Glioblastoma Cells Into Immune Cells to Attack Cancerous Tumors

Converts Cancer Cells to Immune Cells that Recruit Body’s Own Immune System to Target Brain Tumors This immunotherapy directly reprograms cancer cells into immune cells, specifically dendritic cells, making the reprogrammed cancer cells a therapy for the rest of the tumor. Glioblastoma (GBM) is the most common and lethal brain cancer in adults....

Published: 6/27/2021 | Inventor(s): David Tran, Son Le

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Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Human Health Care > Gene Therapy

An engineered pill (aka lab-on-a-pill) for spatial sampling of microbiome and other contents in the gut

SUMMARYTufts researchers have developed a device which traverses the gut and collects samples of the microbiome in a way that permits correlation of samples with particular locations from which they were sampled.BACKGROUNDMore than 1,000 species of bacteria inhabit the healthy gut. The vast majority of these bacteria have a beneficial, supportive role...

Published: 6/10/2022 | Inventor(s): Sameer Sonkusale

Keywords(s):

Category(s): Device

Smart Fabrics

SUMMARYResearchers at Tufts University have developed an implantable, conductive nanothread platform capable of making enhanced measurements of multiple physiological parameters simultaneously and continuously, and reporting these measurements wirelessly. BACKGROUNDSmart devices have changed how we interact with every aspect of our lives, including...

Published: 9/30/2020 | Inventor(s): Sameer Sonkusale, Rachel Owyeung

Keywords(s):

Category(s): Materials, Diagnostic

Liquid Biopsy Screening for Early Detection of Cancers in Patients

Highly Sensitive, Specific and Low Cost Method of Detecting Cancer in Bodily Fluids by Analyzing the Accessibility and Expression of Cancer Master Gene RegulatorsThis non-invasive method of liquid biopsy screening much more sensitively and specifically detects cancer in patients, including those with rare or novel mutations with cost in the order of...

Published: 6/27/2021 | Inventor(s): David Tran, Son Le

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics

Adaptive System that Records Cellular Lineage, Cellular Clock, and Cellular Memory Simultaneously

Diary Reveals a Comprehensive History of a Cell that Aids Research, Diagnostics, and TherapeuticsThis molecular cell diary system is capable of creating a detailed understanding of a cell’s history and current state, including its cellular lineage, cellular clock, and cellular memory. The molecular diagnostics market in 2014 was globally worth...

Published: 6/27/2021 | Inventor(s): David Tran, Son Le

Keywords(s): cellular barometer, cellular clock, cellular events tracking, cellular memory, lineage tracing, mutational history

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Research Tools > Diagnostics, Technology Classifications > Research Tools > Others, Technology Classifications > Research Tools > Vectors, Technology Classifications > Software > Others

Algorithm for Ranking Master Regulators in Gene Networks

Bioinformatics Program Quantifies Influence by Assigning Importance Scores to Nodes in NetworksThis network ranking system uses a computational algorithm based on a set of parameters to generate an importance score for each node in a network, thereby establishing the means to rank and identify master regulators, in particularly transcription factors,...

Published: 6/27/2021 | Inventor(s): David Tran, Son Le

Keywords(s): computational biology, master regulator ranking, node scoring, random network generation, Software

Category(s): Technology Classifications > Software > Others

Glioblastoma Stem Cell Regulators with Therapeutic Potential

Targets Crucial Cancer Stem Cell Factors to Inhibit Glioblastoma Growth This combination of cancer master regulators enables targeting glioblastoma (GBM) stem cells to inhibit their growth. According to the National Brain Tumor Society, only 5.5 percent of patients suffering from GBM survive five or more years after diagnosis, due to rapid cell growth...

Published: 6/27/2021 | Inventor(s): David Tran, Son Le

Keywords(s): cancer drug targets, GBM, GBM stem cells, Glioblastoma, master regulators, stemness

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Therapeutics

Flexible Parylene Metamaterials

BACKGROUNDTerahertz radiation is useful for a variety of applications. For example, because of its ability to penetrate most clothing, terahertz radiation provides a way to detect concealed weapons. Because of its ability to detect differences in water content and density of tissue, terahertz radiation can be used to reliably distinguish between normal...

Published: 6/4/2020 | Inventor(s): Sameer Sonkusale, Willie Padilla, Mehmet Dokmeci

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Category(s): Communications: wireless, Sensors

Metamaterial / pHEMT Hybrid Devices for Terahertz Sources, Modulators and Detectors

BACKGROUNDBetween the optical frequencies and the microwave frequencies is a broad expanse of spectrum in the terahertz range. However, development of devices for operation in the terahertz range is hampered, to some extent, by a dearth of devices for manipulating or detecting terahertz waves.Terahertz radiation is useful for a variety of purposes,...

Published: 6/4/2020 | Inventor(s): Sameer Sonkusale, Saroj Rout, Willie Padilla

Keywords(s):

Category(s): Sensors, Communications: wireless

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