Search Results - photodynamic+therapy

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Near-IR Light-Cleavable Antibody Conjugates and Conjugate Precursors
Abstract: This invention describes a general way to trigger the release of a bioactive small molecule from a targeting antibody. The key “trigger” is a fluorescent linker that is chemically disassembled upon irradiation with light in the near-IR range (~800 nm). This linker technology is a dramatic step forward for the field. The molecules can be tracked...
Published: 4/8/2024   |   Inventor(s): Martin Schnermann, Alexander Gorka, Hisataka Kobayashi, Roger Nani
Keywords(s): ADC, Antibody-drug Conjugate, Chemical linkers, Fluorescent linker, PDT, personalized medicine, Photodynamic therapy, Targeted drug release, Targeted therapy
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics
Exosome-Delivered Targeting Treatment for Blood Vessels
Reference #: 01455 The University of South Carolina is offering licensing opportunities for exosome-delivered targeting treatment for blood vessels Background: Vascular malformations cause a variety of severe symptoms, depending on body location and types of vasculatures involved, which makes clinical management very challenging. The treatment options...
Published: 9/4/2022   |   Inventor(s): Wenbin Tan, Rong Yin, Li Meng
Keywords(s): congenital vascular anomalies, exosomes, laser, photodynamic therapy, targeting treatment
Category(s): Health Sciences, Biomedical and Life Sciences
Sensor and assay for screening of photosensitizers in living cells
Project ID: D2018-33Background Photodynamic therapy (PDT) uses light and a photosensitizer in the presence of oxygen to elicit cell death. This technique has been under investigation for use in treatment of cancerMost often used to treat skin cancer, mycosis fungoides, and non-small cell lung cancer. Researchers need to detect the ability of PDTs to...
Published: 6/18/2024   |   Inventor(s): Welivitiya "Ajith" Karunarathne, Kasun Ratnayake
Keywords(s): PD2, Photodynamic therapy, Photosensitizer, PIP2
Category(s): Neuroscience, Tools