Search Results - margaret+wheatley

7 Results Sort By:
Echogenic Polymer microcapsules and nanocapsules and methods for production and use thereof
PAGE TITLEOverviewPAGE SUMMARY Methods for producing echogenic polymer microcapsules and nanocapsules for use in diagnostic imaging and delivery of bioactive compounds as well as targeted imaging and delivery to selected tissues and cells are provided. Compositions containing these echogenic polymer microcapsules and nanocapsules for use in diagnostic...
Published: 7/11/2024   |   Inventor(s): Margaret Wheatley, Dalia El-Sherif
Keywords(s): Cancer therapeutic
Category(s): Medical Devices & Diagnostics, Pharmaceuticals & Therapeutics, Materials & Chemicals, Materials & Chemicals > M-C: Polymers, Medical Devices & Diagnostics > MDD: Imaging, Pharmaceuticals & Therapeutics > Pharma: Drug Delivery
Gas Filled Surfactant Microbubbles (Joint w/ Drexel. Drexel is the lead)
Surfactant Microbubbles and Process for Preparing and Methods of Using the SameBackground & Summary It has been well documented that chronically hypoxic tumor microenvironments result in both chemotherapy and radiation therapy resistance and pose a major hurdle for effective radiation therapy. In addition, therapy resistance is more pronounced at...
Published: 5/20/2024   |   Inventor(s): John Eisenbrey, Flemming Forsberg, Patrick O'Kane, Margaret Wheatley, Lorenzo Albala
Keywords(s):  
Category(s): Therapeutics, Cancer
Stabilized Ultrasound Contrast Agent
PAGE TITLEOverviewPAGE SUMMARY Provided is a particle-stabilized ultrasound contrast agentn (UCA) and methods of preparing same. Also provided is a method for preparing a lyoprotected UCA, a freeze-dried lyoprotected UCA, and a reconstituted freeze-dried lyoprotected UCA.IP STATUSIntellectual Property and Development StatusUnited States Patent Pending-...
Published: 7/11/2024   |   Inventor(s): Margaret Wheatley, Boriphat Methachan, Carl Solis
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Pharmaceuticals & Therapeutics, Materials & Chemicals, Materials & Chemicals > M-C: Polymers, Medical Devices & Diagnostics > MDD: Imaging, Pharmaceuticals & Therapeutics > Pharma: Drug Delivery
Drug Loaded Contrast Agents: Combining Diagnosis and Therapy
PAGE TITLEOverviewPAGE SUMMARY This invention provides an improvement to methods of drug loading of ultrasound contrast agents. Echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof produced by the method of the invention wherein the echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof contain at least...
Published: 5/19/2022   |   Inventor(s): Margaret Wheatley, Dalia El-Sherif, John Eisenbrey, Odelia Burstein
Keywords(s): Diagnostic ultrasound
Category(s): Pharmaceuticals & Therapeutics, Medical Devices & Diagnostics, Materials & Chemicals, Materials & Chemicals > M-C: Polymers, Medical Devices & Diagnostics > MDD: Imaging, Pharmaceuticals & Therapeutics > Pharma: Drug Delivery
Hollow Polymer Microcapsules and Method of Producing the Same
PAGE TITLEOverview PAGE SUMMARY Hollow polymer microcapsules are made by the method of dissolving a film-forming polymer in a volatile nonaqueous solvent; dispersing into the polymer solution finely divided particles of a volatilizable solid core material; inducing formation of a solid polymer coating on the particulate solid core material in the nonaqueous...
Published: 5/19/2022   |   Inventor(s): Margaret Wheatley, Padma Narayan
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Materials & Chemicals, Medical Devices & Diagnostics, Materials & Chemicals > M-C: Polymers, Medical Devices & Diagnostics > MDD: Imaging, Pharmaceuticals & Therapeutics > Pharma: Drug Delivery
Enhancing radiation therapy sensitivity by overcoming tumor hypoxia
PAGE TITLEOverviewPAGE SUMMARYBiomedical engineers and physicians at Drexel University and The Thomas Jefferson University have developed a new method for targeted delivery of oxygen to solid tumors to enhance the sensitivity of radiation therapy. Focused radiation therapy is frequently used in the treatment of breast and numerous other cancers to...
Published: 8/27/2024   |   Inventor(s): Margaret Wheatley, Lorenzo Albala, Patrick O'kane, Flemming Forsberg, John Eisenbrey
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Pharmaceuticals & Therapeutics, Materials & Chemicals, Materials & Chemicals > M-C: Polymers, Medical Devices & Diagnostics > MDD: Imaging, Pharmaceuticals & Therapeutics > Pharma: Drug Delivery
Porous Polymer Scaffolds for Neural Tissue Engineering and Method of Producing the Same
PAGE TITLEOverviewPAGE SUMMARY The present invention relates to scaffolds that can physically guide cells, e.g. neurons, while best matching the material properties of native tissue. The present invention also relates to methods of generating such scaffolds, and for the use of such scaffolds, e.g. in spinal cord and peripheral nerve injury repair. The...
Published: 7/12/2024   |   Inventor(s): Margaret Wheatley, Ulrike Wegst, Benjamin Riblett, Nicola Francis, Amalie Donius
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Materials & Chemicals, Materials & Chemicals > M-C: Polymers, Medical Devices & Diagnostics > MDD: Implantable/Prosthetic Devices