Search Results - research+tools+%26+materials

13 Results Sort By:
Customizable genomic sequencing library Generation
PAGE TITLE Overview PAGE SUMMARY This innovation is a high-accuracy, low-cost, customizable genome sequencing method compatible with several long-read sequencing systems. It can be used to tailor target specific genomic sequencing increasing custom product offerings for sequencing service provider and kit manufacturer customers. This technology...
Published: 10/31/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Research Tools & Materials, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Life Sciences
Tools for Genomic Applications Powered by CRISPR/CAS9 Based DNA Labeling
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Drexel has a portfolio of tools and platforms for genomics applications based on the CRISPR/CAS9 system. The portfolio has applications in clinical diagnostics, cell and gene therapy, and genomics research among others. We are seeking licensing partners to translate the platforms and diagnostic...
Published: 8/5/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Pharmaceuticals & Therapeutics > Pharma: Oncology, Research Tools & Materials
Telomere assay for the detection of alternative lengthening of telomere (ALT) activity in cells
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A unique tool for distinguishing cancer cells based on telomere maintenance mechanisms, providing potential biomarkers for cancer subtypes and therapeutic responses. Description: This technology provides detailed telomere profiling from individual chromosomes, capable of differentiating...
Published: 6/28/2024   |   Inventor(s): Ming Xiao
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Quantification of On-off target gene editing by optical mapping
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A revolutionary methodology for quantifying on-target and off-target gene editing activity using CRISPR-Cas9 and optical mapping. Description: This technology comprises a single-molecule optical mapping strategy using CRISPR-Cas9 to fluorescently label the modified genes. The method involves...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Yilin Wang, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Research Tools & Materials, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering
Multicolor whole-genome mapping for genetic analysis
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A novel method for precise genome mapping and sequencing using Cas9-mediated labeling within nanochannels. Description: This technology is a method for mapping a whole genome using a universal multi-color mapping strategy in nanochannels that combines a conventional sequence-motif labeling...
Published: 6/20/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Linked-read sequencing library preparation
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Innovative methods for generating sequence-linked DNA fragments for high-quality, low-cost genome sequencing. Description: This technology describes a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal duplications. The...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Research Tools & Materials
Single molecule real-time long DNA mapping and sequencing
PAGE TITLE Overview PAGE SUMMARY Executive Statement: The invention offers an innovative way to immobilize and optically map/sequence oligonucleotides on a micropatterned substrate for efficient large-scale genomic assembly. Description: This technology presents a method for immobilizing and linearizing oligonucleotides on a micropatterned...
Published: 6/20/2024   |   Inventor(s): Ming Xiao, Dharma Varapula, Eric LaBouff, Moses (hongseok) Noh
Keywords(s):  
Category(s): Medical Devices & Diagnostics, Computing, Software, Analytics & Information Technology > Computing: Bioinformatics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Life Sciences, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Nanotube-based sensors and probes
PAGE TITLE Overview PAGE SUMMARY Described herein are novel devices for the study of transport characteristics of complex or simple fluids, interactions among molecules in suspension, interactions between molecules in suspension and wall-bound molecules, and biochemical sensing devices made of reservoirs for fluid containment linked by a nanotubes....
Published: 8/12/2024   |   Inventor(s): Yury Gogotsi, Byong Man Kim, Michael Riegelman, Haim Bao
Keywords(s):  
Category(s): Materials & Chemicals, Medical Devices & Diagnostics, Research Tools & Materials, Materials & Chemicals > M-C: Nanomaterials, Materials & Chemicals > M-C: Micro & Nanotech, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Hardware, Circuits & Sensors, Hardware, Circuits & Sensors > Hardware: Biological Sensors, Hardware, Circuits & Sensors > Hardware: Chemical Sensors
Electroencephalogram-Based Estimation of Brain Age
PAGE TITLEFunctional Brain Age Estimation Via Resting State EEG PAGE SUMMARYThe early detection and quantification of abnormal brain changes are important for the prospective identification and subsequent treatment of individuals at risk for various neurological disorders, injuries, and cognitive decline. Discrepancies between an individual’s...
Published: 8/5/2021   |   Inventor(s): John Kounios, Fengqing Zhang, Jessica Fleck
Keywords(s):  
Category(s): Research Tools & Materials, Medical Devices & Diagnostics, Digital Health & Healthcare IT, Medical Devices & Diagnostics > MDD: Imaging, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Digital Health & Healthcare IT > Dig. Health: Imaging, Digital Health & Healthcare IT > Dig. Health: Psychology
Flow chamber and analyte detection method
PAGE TITLE Overview PAGE SUMMARY Researchers in the School of Biomedical Engineering at Drexel University have developed a flow chamber and method for detecting the presence of one or more cell-produced analytes under flow conditions. The parallel-plate flow chamber has two components separated by a permeable membrane, with one compartment containing...
Published: 7/22/2024   |   Inventor(s): Kenneth Barbee, Dov Jaron, Allison Andrews
Keywords(s):  
Category(s): Research Tools & Materials, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Medical Devices & Diagnostics > MDD: Point of Care Diagnostics
1 2