Search Results - pediatric

5 Results Sort By:
Chimeric Antigen Receptors to CD22 for Treating Hematological Cancers
Abstract: Chimeric antigen receptors (CARs) are hybrid proteins consisting of an antibody binding fragment fused to protein signaling domains that cause T-cells which express the CAR to become cytotoxic.  Once activated, these cytotoxic T-cells can selectively eliminate the cells which they recognize via the antibody binding fragment of the CAR.  Thus,...
Published: 4/8/2024   |   Inventor(s): Rimas Orentas, Nirali Shah, Ira Pastan, Crystal Mackall, Dimiter Dimitrov
Keywords(s): Acute Lymphoblastic Leukemia, adoptive cell therapy, ALL, B-CELL, CD22, Chimeric antigen receptors (CARs), Chronic lymphocytic leukemia, CLL, Dimitrov, Hairy cell leukemia, HCL, Immunotherapy, pediatric
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics
Robotic Exoskeleton for Treatment of Crouch Gait in Children with Cerebral Palsy (CP)
Abstract: Crouch gait is a common disorder in pediatric cerebral palsy (CP). Effective treatment of crouch during childhood is critical to maintain mobility into adulthood. Current interventions do not alleviate crouch gait long-term for most patients. This technology relates to a powered exoskeleton designed for gait assistance. The powered assistance...
Published: 4/8/2024   |   Inventor(s): Thomas Bulea, Zachary Lerner, Diane Damiano, Andrew Gravunder
Keywords(s): cerebral palsy, Crouch gait, Exoskeleton, Lerner, National Institute of Health Clinical Center (NIHCC), NEURODEGENERATIVE, Northern Arizona University (NAU), pediatric, Robotic Exoskeleton
Category(s): Collaboration Sought > Licensing, Application > Medical Devices, Collaboration Sought > Collaboration, Application > Non-Medical Devices
Diagnosis and Treatment of Pediatric Acute Neurologic Syndrome with Antineuronal Antibodies
The invention is a panel of five tests of patient sera for immune responses that may attack the brain and lead to the characteristic symptoms of pediatric acute neurologic syndrome (PANS). PANS is a condition defined by a sudden onset of obsessive-compulsive symptoms, eating restrictions, and other cognitive and/or behavioral symptoms. Currently, the...
Published: 10/28/2024   |   Inventor(s): Susan Swedo, Christine Kirvan, Madelein Cunningham
Keywords(s): ACUTE, antibodies, Antineuronal, Diagnosis, Listed LPM Greene as of 4/15/2015, Neurologic, pediatric, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Syndrome, treatment, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XAXXXX, XCXXXX
Category(s): TherapeuticArea > Psychiatry/Mental Health, TherapeuticArea > Neurology, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics, ResearchProducts > Antibodies
A Multidimensional Real-Time Pain Monitoring System
ApplicationsThis invention relates to monitoring pain and distress in premature infants and in other non-communicative populations such as critically ill and those cognitively impaired. It would also potentially have broad applications for parental monitoring of new born infants. The proposed system would automatically measure multiple parameters and...
Published: 5/7/2024   |   Inventor(s): Martin Schiavenato, Laurel Carney, Scott Seidman
Keywords(s): Neonatology, NICU, Pediatric
Category(s): Diagnostic, Devices, Communications, Informatics
Pediatric Blood Pressure Screening Wheel
Applications:This is a copyrighted screening wheel with potential for widespread use in screening for high blood pressure in children.Advantages:The current method for determining if a child has elevated blood pressure is very cumbersome. It involves plotting a height percentile on a CDC growth chart and then looking at a complicated table for the...
Published: 5/23/2023   |   Inventor(s): Megan Rashid
Keywords(s): Diagnostic, Pediatric
Category(s): Therapeutic