Search Results - patrick+duffy

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A Novel Strategy to Produce 6-cys Proteins Based on Pfs230D1 Domain Fusions
The Plasmodium parasite has a complex lifecycle during human infection and in the mosquito vector. Most advanced malaria vaccine candidates can confer only partial, short-term protection in malaria-endemic areas. A means of breaking the transmission of malaria to subsequent individuals could prevent a significant amount of human disease. The primary...
Published: 5/8/2025   |   Inventor(s): Patrick Duffy, Jonathan Renn
Keywords(s):  
Category(s): Application, Application > Research Materials, Application > Therapeutics, Application > Vaccines, Collaboration Sought, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, ResearchProducts > Sequences, TherapeuticArea > Immunology, TherapeuticArea > Infectious Disease
Plasmodium liver stage antigens
PAGE TITLE Plasmodium liver stage antigens for malaria vaccine and diagnostics PAGE SUMMARY There are an estimated 200-300 million people infected with malaria annually, with a mortality rate of 1-3%, and 40% of the world’s population at risk of contracting the disease. While the RTS,S (Mosquirix, GSK) recombinant protein-based vaccine is...
Published: 2/19/2025   |   Inventor(s): Lawrence Bergman, Stefan Kappe, Patrick Duffy, Urszula Krzych, Donald Heppner, Vladislav Malkov, Alice Tarun, Jason Wendler, Igor Bacik
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics