Search Results - lawrence+bergman

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Mechanism-based small-molecule parasite inhibitors
PAGE TITLESmall molecule inhibitors of Plasmodium falciparum for antimalarial therapyPAGE SUMMARY There are an estimated 200 million people infected with malaria annually, with an estimated 400,000-500,000 deaths, and 40% of the world’s population at risk of contracting the disease. While artemisinin and mosquito reduction are the current treatments,...
Published: 8/27/2024   |   Inventor(s): Lawrence Bergman, Akhil Vaidya, William Welsh, Sandhya Kortagere
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Infectious Disease, Pharmaceuticals & Therapeutics > Pharma: Malaria
Plasmodium liver stage antigens
PAGE TITLE Plasmodium liver stage antigens for malaria vaccine and diagnostics PAGE SUMMARY There are an estimated 200-300 million people infected with malaria annually, with a mortality rate of 1-3%, and 40% of the world’s population at risk of contracting the disease. While the RTS,S (Mosquirix, GSK) recombinant protein-based vaccine is...
Published: 7/22/2024   |   Inventor(s): Lawrence Bergman, Stefan Kappe, Patrick Duffy, Urszula Krzych, Donald Heppner, Vladislav Malkov, Alice Tarun, Jason Wendler, Igor Bacik
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Infectious Disease, Pharmaceuticals & Therapeutics > Pharma: Malaria
Use of cymanquine compounds as antimalarial agents
PAGE SUMMARY There are an estimated 200-300 million people infected with malaria annually, with a mortality rate of 1-3%, and 40% of the world’s population at risk of contracting the disease. While artemisinin and mosquito reduction are the current treatments, there are drug-resistant parasites emerging, underscoring the need for the next generation...
Published: 8/1/2024   |   Inventor(s): Lawrence Bergman, William Geiger, Kevin Lam
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Infectious Disease, Pharmaceuticals & Therapeutics > Pharma: Malaria