Search Results - oligonucleotides

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SINGLE-CELL CULTURE AND SEQUENCING WITH LIPID-MODIFIED OLIGOS
SINGLE-CELL CULTURE AND SEQUENCING WITH LIPID-MODIFIED OLIGOS Researchers at UCSF have developed methods for sequencing a single cell from a cell culture sample and obtaining morphologic or phenotypic measurements and information by combining sequencing approaches and spatial hashing (e.g. barcoding) at a single cell level. There exists a need in...
Published: 7/27/2023   |   Inventor(s): Kai-Chun Chang, Adam Abate
Keywords(s): Lipid-Modified, Oligonucleotides, Sequencing, Single Cell
Category(s): Technology Classifications > Biology
A Method to Expand a Population of Regulatory T Cells Optimal for the Treatment of Autoimmune Diseases
The transfusion of regulatory T cells (Tregs) has been used in the clinic to successfully prevent graft vs. host disease and is currently being evaluated in the treatment of other autoimmune diseases, such as organ graft rejection, type 1 diabetes and multiple sclerosis. Prior to transfusion, adoptive regulatory T cell transfer requires the expansion...
Published: 10/28/2024   |   Inventor(s): Ethan Shevach, Yong Chan Kim
Keywords(s): Cells, FOXP3+, Helios-expressing, Human, IBXXXX, IDXXXX, IXXXXX, oligonucleotides, Random-sequenced, Regulatory, Stabilization, T, Usingrandom-sequenced
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics