Search Results - daniel+davis

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KinetiSol powder ejection for low-temperature formulation of thermolabile APIs
Background Many emerging drug candidates suffer from poor aqueous solubility and heat sensitivity, making them difficult to formulate using conventional manufactur­ing techniques. These challenges are especially problematic for inhalation and nasal drug delivery, where fine particle size and chemical stability are essential for therapeutic performance. Existing...
Published: 2/3/2026   |   Inventor(s): Robert Williams, Miguel Jara Gonzalez, Beatriz Behrend, Daniel Davis, Dave Miller
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Solvent-free enhanced 3D printing of biologics
Background/problem 3D printing holds great potential for creating personalized medication and pharmaceutical dosage forms. However, it faces challenges when using powder bed-based technologies like Selective Laser Sintering (SLS) and Binder Jetting. These methods require powders with excellent flow characteristics to function smoothly. This is a straightforward...
Published: 1/13/2026   |   Inventor(s): Mohammed Maniruzzaman, Joseph Beaman, Robert Williams, Timothy Phillips, Rishi Thakkar, Amit Pillai, Daniel Davis
Keywords(s):  
Category(s): Life sciences > Research tools
3D printing technology for customized pharmaceutical dosage forms
The invention utilizes 3D printing with selective laser sintering to create pharmaceutical tablets from amorphous solid dispersions, enhancing drug solubility and bioavailability without additional excipients, allowing customizable drug release rates and unique dosage forms. Background In the pharmaceutical industry, the development of drugs with...
Published: 1/13/2026   |   Inventor(s): Mohammed Maniruzzaman, Robert Williams, Daniel Davis, Rishi Thakkar
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Processes and compositions to expand drug processing
Background Dr. Robert O. Williams III and his team have developed a method to expand the ability of the hot-melt extrusion process to increase drug loading in amorphous solid dispersions (ASD). Dr. Williams is the Division Head and Professor of Molecular Pharmaceutics and Drug Delivery and the Johnson & Johnson Centennial Chair in Pharmacy at UT...
Published: 1/13/2026   |   Inventor(s): Robert Williams, Daniel Davis, Stephen Thompson
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Research tools > Reagent
Efficient 3D printing manufacturing platform for poorly soluble drugs
Novel 3D printing approach enables single-step manufacturing of poorly soluble drugsBackgroundA large number of pharmaceuticals are eliminated by the body due to their poor water solubility. This limits effectiveness because the drugs cannot be efficiently absorbed. To overcome this, drugs can be administered in an amorphous state rather than a crystalline...
Published: 1/13/2026   |   Inventor(s): Robert Williams, Daniel Davis, Mohammed Maniruzzaman, Rishi Thakkar
Keywords(s): 3D printing, Manufacturing, Pharmaceuticals
Category(s): Life sciences > Therapeutics > Drug delivery