Search Results - leah+wilson

10 Results Sort By:
Personalized type 1 diabetes decision support using digital twins
Summary The current technology is the first decision support tool for type 1 diabetes that provides personalized recommendations based on digital twin simulations and accounts for variables such as carbohydrate consumption, exercise, and nighttime risk of hypoglycemia. Technology Overview Managing glucose levels is challenging for individuals with...
Published: 12/13/2024   |   Inventor(s): Peter Jacobs, Clara Mosquera-Lopez, Leah Wilson, Gavin Young
Keywords(s): Software
Category(s): Software
Meal detection and size estimation for artificial pancreas devices using machine learning
­Summary The current technology can be used within an automated insulin delivery system to automate insulin delivery (AID) in response to meals. This technology has the potential to reduce the burden of a person living with type 1 diabetes using an AID and potentially improving glucose management by accurately and automatically delivering insulin...
Published: 9/19/2023   |   Inventor(s): Clara Mosquera-Lopez, Peter Jacobs, Leah Wilson, Jessica Castle
Keywords(s): Automation, Connected Devices, Software, Software - Other
Category(s): Software
DailyDose decision support smart phone app to improve glycemic control in type 1 diabetes (T1D)
Summary A smart phone application and graphical user interface, which provides real-time dosing advice and weekly insulin dose adjustments to improve glucose management in patients with type 1 diabetes using daily insulin injections. Technology Overview Close to 1.5 million people in the US have type 1 diabetes and many have difficulty managing their...
Published: 9/27/2023   |   Inventor(s): Peter Jacobs, Joseph Pinsonault, Jessica Castle, Joseph El Youssef, Sos Oganessian, Leah Wilson
Keywords(s): Software, Software - Diagnostic/Detection
Category(s): Software
Nocturnal hypoglycemia prediction algorithm
Summary This hypoglycemia prediction algorithm calculates the risk of possible hypoglycemic episodes before the patient goes to bed. Technology Overview Utilizing a support regression algorithm (SVR) to predict minimum glucose levels and a decision theory/cost-benefit analysis to estimate nocturnal glucose alert levels, this algorithm predicts nighttime...
Published: 9/20/2023   |   Inventor(s): Peter Jacobs, Clara Mosquera-Lopez, Nichole Tyler, Robert Dodier, Jessica Castle, Joseph El Youssef, Leah Wilson
Keywords(s): Software, Software - Other
Category(s): Software
Immunotherapy That Converts Glioblastoma Cells Into Immune Cells to Attack Cancerous Tumors
Converts Cancer Cells to Immune Cells that Recruit Body’s Own Immune System to Target Brain Tumors This immunotherapy directly reprograms cancer cells into immune cells, specifically dendritic cells, making the reprogrammed cancer cells a therapy for the rest of the tumor. Glioblastoma (GBM) is the most common and lethal brain cancer in adults....
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Human Health Care > Gene Therapy
DailyDose decision support algorithm to improve glycemic control
Summary The DailyDose algorithm provides an artificial intelligence decision support system for improved management of blood glucose in patients with type 1 diabetes using multiple daily injection therapy. Technology Overview Up to 40% of patients with type 1 diabetes use multiple daily injections of insulin to manage their condition; however, dosing...
Published: 9/27/2023   |   Inventor(s): Peter Jacobs, Jessica Castle, Joseph El Youssef, Clara Mosquera-Lopez, Nichole Tyler, Robert Dodier, Leah Wilson
Keywords(s): Software, Software - Other
Category(s): Software
Liquid Biopsy Screening for Early Detection of Cancers in Patients
Highly Sensitive, Specific and Low Cost Method of Detecting Cancer in Bodily Fluids by Analyzing the Accessibility and Expression of Cancer Master Gene RegulatorsThis non-invasive method of liquid biopsy screening much more sensitively and specifically detects cancer in patients, including those with rare or novel mutations with cost in the order of...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics
Adaptive System that Records Cellular Lineage, Cellular Clock, and Cellular Memory Simultaneously
Diary Reveals a Comprehensive History of a Cell that Aids Research, Diagnostics, and TherapeuticsThis molecular cell diary system is capable of creating a detailed understanding of a cell’s history and current state, including its cellular lineage, cellular clock, and cellular memory. The molecular diagnostics market in 2014 was globally worth...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s): cellular barometer, cellular clock, cellular events tracking, cellular memory, lineage tracing, mutational history
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Research Tools > Diagnostics, Technology Classifications > Research Tools > Others, Technology Classifications > Research Tools > Vectors, Technology Classifications > Software > Others
Algorithm for Ranking Master Regulators in Gene Networks
Bioinformatics Program Quantifies Influence by Assigning Importance Scores to Nodes in NetworksThis network ranking system uses a computational algorithm based on a set of parameters to generate an importance score for each node in a network, thereby establishing the means to rank and identify master regulators, in particularly transcription factors,...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s): computational biology, master regulator ranking, node scoring, random network generation, Software
Category(s): Technology Classifications > Software > Others
Glioblastoma Stem Cell Regulators with Therapeutic Potential
Targets Crucial Cancer Stem Cell Factors to Inhibit Glioblastoma Growth This combination of cancer master regulators enables targeting glioblastoma (GBM) stem cells to inhibit their growth. According to the National Brain Tumor Society, only 5.5 percent of patients suffering from GBM survive five or more years after diagnosis, due to rapid cell growth...
Published: 6/27/2021   |   Inventor(s): David Tran, Son Le
Keywords(s): cancer drug targets, GBM, GBM stem cells, Glioblastoma, master regulators, stemness
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Therapeutics