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Search Results - john+lueck
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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023
|
Inventor(s):
Jianfeng Cai
,
Shibo JIANG
,
Lu LU
,
Songyi XUE
,
Xinling WANG
,
Lei WANG
,
Wei XU
,
Shuai XIA
Keywords(s):
Drug Discovery
,
Immunology
Category(s):
Technology Classifications > Medical > Biotechnology
A method for treating a myotonic disorder
Background Myotonic disorders are a group of genetic diseases characterized by the presence of myotonia, which is defined as failure of muscle relaxation after activation. The presentation of these disorders can range from asymptomatic electrical myotonia, as seen in some forms of myotonia congenita (MC), to severe disability with muscle weakness,...
Published: 5/7/2024
|
Inventor(s):
John Lueck
,
Charles Thornton
,
Lily Cisco
Keywords(s):
Category(s):
Therapeutic
Platform of engineered tRNAs that target and suppress disease caused by nonsense mutations
Background Nonsense mutations, or premature termination codons (PTCs), make up 10-15% of all genetic diseases, affecting over 30 million people worldwide through 7,000 different diseases. Currently, there are very limited options for their therapeutic management. Some of the available agents have significant issues such as off-target toxicity and low...
Published: 5/7/2024
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Inventor(s):
John Lueck
,
Joseph Porter
,
Charles Thornton
,
Wooree Ko
Keywords(s):
Category(s):
Research Tools
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024
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Inventor(s):
Soung Chang Liew
,
Lu LU
,
Lizhao You
Keywords(s):
Network Coding
,
Wireless Local Area Network
Category(s):
Information and Communications Technology