Search Results - jiaqing+zhou

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Allosteric Inhibitors of the Main Protease of SARS-CoV-2

In this report, the SARS-CoV-2 3CLpro was expressed and purified. By using a FRET-based enzymatic assay, the researchers have screened a library consisting of more than 300 different niclosamide derivatives and identified three molecules JMX0286, JMX0301, and JMX0941 as potent allosteric inhibitors against SARS-CoV-2 3CLpro, with IC50 values like that...

Published: 4/1/2024 | Inventor(s): Hongmin Li, subodh samrat, Zhong Li, Jia Zhou, Jimin Xu

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Infectious Diseases

Reactor for Bulk Manufacturing of Core-Shell Quantum Dot Nanoparticles

Enables Large-Scale Production of Precision Quantum Dots for Medical Imaging, LEDs and Solar CellsThis multi-variable reactor facilitates the manufacturing of high-precision, core-shell quantum dots - nanoparticles made from semiconductive materials that display unique optical and electrical properties. Quantum dots have applications in computing, photovoltaic...

Published: 6/27/2021 | Inventor(s): Spyros Svoronos, Brij Moudgil, Kevin Powers, Paul Carpinone, Parvesh Sharma, Ajoy Saha, Jiaqing Zhou, Michelle Powers, Gary Scheiffele

Keywords(s): Core Shell, Flow Manufacturing, Hydrothermal, quantum dots

Category(s): Technology Classifications > Engineering, Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials, Technology Classifications > Others > Cleantech

Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis

Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...

Published: 3/23/2023 | Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia

Keywords(s):

Category(s): BioPharma