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Search Results - jimin+xu
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Allosteric Inhibitors of the Main Protease of SARS-CoV-2
In this report, the SARS-CoV-2 3CLpro was expressed and purified. By using a FRET-based enzymatic assay, the researchers have screened a library consisting of more than 300 different niclosamide derivatives and identified three molecules JMX0286, JMX0301, and JMX0941 as potent allosteric inhibitors against SARS-CoV-2 3CLpro, with IC50 values like that...
Published: 4/1/2024
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Inventor(s):
Hongmin Li
,
subodh samrat
,
Zhong Li
,
Jia Zhou
,
Jimin Xu
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Healthcare Portfolios
,
Technology Classifications > Healthcare Portfolios > Infectious Diseases
Methods for Modeling Water Quality
The Problem: Monitoring and mapping inland water quality is critical for sustainability of water supplies for human consumption, agriculture, industry, and other economic activities. In previous studies, empirical models have been widely used to map water quality parameters for inland waters using remotely sensed imagery. Due to the complex...
Published: 6/2/2023
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Inventor(s):
Hongxing Liu
,
Min Xu
,
Richard Beck
Keywords(s):
Category(s):
Technology Classifications > Communication
,
Technology Classifications > Systems & Services