Search Results - jianyuan+zhang

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Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications. Background Producing micro- and nanoparticles for pharmaceutical and...
Published: 1/7/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Safe Explicable Robot Planning
Background Effective human-robot interaction must be informed by human expectations and knowledge of the world, including how robots are expected to act/interact in various situations. However, knowledge about the robot may be inconsistent with the ground truth, which can result in the robot not meeting expectations, and the interaction integrity being...
Published: 12/13/2024   |   Inventor(s): Yu Zhang, Akkamahadevi Hanni, Andrew Boateng
Keywords(s):  
Category(s): Physical Science, Applied Technologies, Wireless & Networking, Artificial Intelligence/Machine Learning
A Three-Buckyball Platform to Synthesize Structurally Defined Water-Soluble Metallofullerene Derivatives
​ Invention Summary: Fullerenes, an allotrope of carbon, are polyhedral closed cages. Fullerenes are able to host additional atoms within their inner spheres. Fullerenes hosting electropositive metals (e.g. Sc, Gd, La), known as endohedral metallofullerenes (EMFs), are especially interesting as the encapsulated metals provide additional...
Published: 11/26/2024   |   Inventor(s): Jianyuan Zhang, William Kopcha, Yue Sun, Rohin Biswas, Yanbang Li
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Imaging, Technology Classifications > Nanotechnology
3D-printed biosensors for high-sensitivity molecular detection
This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic
“Bio-Flex”: advanced formulation for sustainable stereolithography (SLA)
Background/problem Stereolithography (SLA) 3D printing has transformed the biomedical field with creation of highly accurate, patient-specific medical devices such as tissue scaffolds, implants, and surgical tools. This technology leverages computer-aided design and medical imaging data to produce structures with precise geometries at submicron scales....
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Anqi Lu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Therapeutics > Drug delivery
Thermal Control During Additive Manufacturing
THE CHALLENGE Additive manufacturing (AM) has emerged as a powerful tool within engineering. Many AM and coating processes rely on thermal input to soften or melt the materials involved in processing. However, this melting or softening typically results in a higher thermal gradient between deposited material and the workpiece, commonly resulting in...
Published: 12/20/2023   |   Inventor(s): Robert Griffiths, David Garcia, Hang Yu
Keywords(s):  
Category(s): EXPERIMENT--DO NOT USE, Technology Classifications > Additive Manufacturing
FIBP Knockout Potentiates Therapeutic Effects of T-cell Based Therapies in Solid Tumors
Abstract: Despite recent breakthroughs in cancer immunotherapy, T-cell based therapies achieve limited efficacy in solid tumors. Immunosuppression, antigen escape and physical barriers to entry into solid tumors are issues faced. Identifying regulators in T-cell dysfunction remains challenging due to limitations of current screening platforms.  Using...
Published: 12/17/2024   |   Inventor(s): Peng Jiang, Yu Zhang
Keywords(s): adoptive cell therapy, Cancer Immunotherapy, cholesterol metabolism, Computational Model, FGF1 Intracellular Binding Protein, FIBP, Jiang, solid tumors, T-Cell based Therapy, T-Cell Resilience
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
Automated Flight Planning System for Urban Air Mobility
Advantages: AFPS uses advanced algorithms for airspace management and conflict resolution, ensuring safety in high-density Urban air mobility (UAM) environments. AFPS enhances UAM efficiency by optimizing airspace use and generating conflict-free flight paths. AFPS allows Providers of Service for UAM (PSU) to provide seamless airspace and traffic...
Published: 9/3/2024   |   Inventor(s): Yu Zhang
Keywords(s): Industrial Applications, Transportation
Category(s): Technology Classifications > Engineering > Drones, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Engineering > Sensors, Technology Classifications > Energy & Environment
Membraneless Method for Electricity Generation from Salinity Gradients
Background Blue energy, which is the Gibbs energy that results from mixing seawater and river water, is a promising source of clean energy. Pressure-retarded osmosis (PRO) and reverse electrodialysis (RED) are currently the most successful methods for extracting such energy. However, their performance is limited by challenging issues associated with...
Published: 5/26/2023   |   Inventor(s): Tianwei Ma, Jian Yu
Keywords(s):  
Category(s): Energy & Power, Environmental, Physical Science, Alternative Energy
Self-Charging Liquid Droplet Capacitor for Harvesting Ambient Energy
­Potential Applications • Self-powered sensors • Biomedical implants • Internet-of-Things (IoT) devices • Remote monitoring • Portable electronics Benefits and Advantages • Exponential increase in harvested energy – Positive feedback by continuous capacitor switching delivers exponentially more...
Published: 2/23/2023   |   Inventor(s): Tianwei Ma, Jian Yu
Keywords(s):  
Category(s): Physical Science, Semiconductor Devices, Alternative Energy, Alternative Energy/Biofuels/Bioplastics/Algae, Energy & Power
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