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Search Results - jianyuan+zhang
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A Three-Buckyball Platform to Synthesize Structurally Defined Water-Soluble Metallofullerene Derivatives
Invention Summary: Fullerenes, an allotrope of carbon, are polyhedral closed cages. Fullerenes are able to host additional atoms within their inner spheres. Fullerenes hosting electropositive metals (e.g. Sc, Gd, La), known as endohedral metallofullerenes (EMFs), are especially interesting as the encapsulated metals provide additional...
Published: 11/5/2024
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Inventor(s):
Jianyuan Zhang
,
William Kopcha
,
Yue Sun
,
Rohin Biswas
,
Yanbang Li
Keywords(s):
Category(s):
Technology Classifications > Physical Sciences & Engineering
,
Technology Classifications > Medical Imaging
,
Technology Classifications > Nanotechnology
3D-printed biosensors for high-sensitivity molecular detection
This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...
Published: 7/26/2024
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Inventor(s):
Mohammed Maniruzzaman
,
Yu Zhang
Keywords(s):
Category(s):
Life sciences > Research tools > Tool/assay/screening platform
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Life sciences > Diagnostic
“Bio-Flex”: advanced formulation for sustainable stereolithography (SLA)
Background/problem Stereolithography (SLA) 3D printing has transformed the biomedical field with creation of highly accurate, patient-specific medical devices such as tissue scaffolds, implants, and surgical tools. This technology leverages computer-aided design and medical imaging data to produce structures with precise geometries at submicron scales....
Published: 7/26/2024
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Inventor(s):
Mohammed Maniruzzaman
,
Yu Zhang
,
Anqi Lu
Keywords(s):
Category(s):
Life sciences > Medical technology > Medical devices
,
Life sciences > Therapeutics > Drug delivery
Thermal Control During Additive Manufacturing
THE CHALLENGE Additive manufacturing (AM) has emerged as a powerful tool within engineering. Many AM and coating processes rely on thermal input to soften or melt the materials involved in processing. However, this melting or softening typically results in a higher thermal gradient between deposited material and the workpiece, commonly resulting in...
Published: 12/20/2023
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Inventor(s):
Robert Griffiths
,
David Garcia
,
Hang Yu
Keywords(s):
Category(s):
EXPERIMENT--DO NOT USE
,
Technology Classifications > Additive Manufacturing
FIBP Knockout Potentiates Therapeutic Effects of T-cell Based Therapies in Solid Tumors
Abstract: Despite recent breakthroughs in cancer immunotherapy, T-cell based therapies achieve limited efficacy in solid tumors. Immunosuppression, antigen escape and physical barriers to entry into solid tumors are issues faced. Identifying regulators in T-cell dysfunction remains challenging due to limitations of current screening platforms. Using...
Published: 4/8/2024
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Inventor(s):
Peng Jiang
,
Yu Zhang
Keywords(s):
adoptive cell therapy
,
Cancer Immunotherapy
,
cholesterol metabolism
,
Computational Model
,
FGF1 Intracellular Binding Protein
,
FIBP
,
Jiang
,
solid tumors
,
T-Cell based Therapy
,
T-Cell Resilience
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
,
Application > Therapeutics
Automated Flight Planning System for Urban Air Mobility
Advantages: AFPS uses advanced algorithms for airspace management and conflict resolution, ensuring safety in high-density Urban air mobility (UAM) environments. AFPS enhances UAM efficiency by optimizing airspace use and generating conflict-free flight paths. AFPS allows Providers of Service for UAM (PSU) to provide seamless airspace and traffic...
Published: 9/3/2024
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Inventor(s):
Yu Zhang
Keywords(s):
Industrial Applications
,
Transportation
Category(s):
Technology Classifications > Engineering > Drones
,
Technology Classifications > Engineering > Mechanical Engineering
,
Technology Classifications > Engineering > Sensors
,
Technology Classifications > Energy & Environment
Membraneless Method for Electricity Generation from Salinity Gradients
Background Blue energy, which is the Gibbs energy that results from mixing seawater and river water, is a promising source of clean energy. Pressure-retarded osmosis (PRO) and reverse electrodialysis (RED) are currently the most successful methods for extracting such energy. However, their performance is limited by challenging issues associated with...
Published: 5/26/2023
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Inventor(s):
Tianwei Ma
,
Jian Yu
Keywords(s):
Category(s):
Energy & Power
,
Environmental
,
Physical Science
,
Alternative Energy
Self-Charging Liquid Droplet Capacitor for Harvesting Ambient Energy
Potential Applications • Self-powered sensors • Biomedical implants • Internet-of-Things (IoT) devices • Remote monitoring • Portable electronics Benefits and Advantages • Exponential increase in harvested energy – Positive feedback by continuous capacitor switching delivers exponentially more...
Published: 2/23/2023
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Inventor(s):
Tianwei Ma
,
Jian Yu
Keywords(s):
Category(s):
Physical Science
,
Semiconductor Devices
,
Alternative Energy
,
Alternative Energy/Biofuels/Bioplastics/Algae
,
Energy & Power
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
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Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Medical Imaging
,
Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Method to Measure Transportation System Performance and Infrastructure Restoration
Competitive Advantages Efficient allocation of time and resources Fast decision making Optimization of multiple factors in capacity-flow transportation Summary USF inventors have created a comprehensive method to assess damages and resilience and efficiently plan repairs and reconstruction of transportation infrastructure. This novel methodology...
Published: 7/12/2023
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Inventor(s):
Tingting Zhao
,
Yu Zhang
Keywords(s):
Category(s):
Technology Classifications > Software
,
Technology Classifications > Computer Science > C/S Transportation
,
Technology Classifications > Computer Science
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