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Automatic Detection and Quantification of Marine Macroalgae from Satellite Imagery

Advantages: Automates seaweed detection and quantification using satellite imagery Combines physics-based models and machine learning for accurate results Generates actionable seaweed maps at various spatial and temporal resolutions Applicable globally works on both Sargassum and Ulva blooms across different regions Summary: Massive seaweed...

Published: 3/28/2025 | Inventor(s): Chuanmin Hu, Mengqiu Wang

Keywords(s):

Category(s): Technology Classifications > Electronics > Electronics Laser, Technology Classifications > Data/AI > D/AI Imaging

Piperlongumine-Based PROTAC As Potent Anticancer Agent With Reduced Toxicity

Uses Piperlongumine as an E3 Ligase Ligand to Facilitate the Degradation of Cancer-Associated Proteins of Interest This naturally occurring compound with anti-cancer properties has the potential to revolutionize cancer treatment by providing tailored therapies with reduced side effects. Cancer remains a significant health issue in the United States,...

Published: 2/26/2025 | Inventor(s): Guangrong Zheng, Daohong Zhou, Dongwen Lyu, Yaxia Yuan, Xingui Liu, Yufeng Xiao, Wanyi Hu, Jing Pei

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Therapeutics

Enterovirus D68 capsid inhibitors as antivirals

Plaque assay results of Jun11-46-1 and Jun11-54-1 against EV-D68 US/MO/14-18947. Invention Summary: Enterovirus D68 (EV-D68) is an RNA virus that mainly affects children and results in moderate to severe respiratory illness, with the most extreme cases resulting in muscle weakness, paralysis, and death. Currently, there are no antivirals...

Published: 1/27/2025 | Inventor(s): Jun Wang, Yanmei Hu, Kan Li

Keywords(s): Antibacterial, Small molecules

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Infectious Disease, Technology Classifications > Therapeutics

Small Molecule Direct Inhibitors of Keap1-Nrf2 Protein-Protein Interaction

Non-covalent direct inhibition of the Keap1-Nrf2 PPI resulting in upregulation of ARE-gene expression. Thus, increase ARE-controlled cytoprotective oxidative stress response enzymes in the development of therapeutic and preventive agents for a number of diseases and conditions. Invention Summary: The Keap1-Nrf2-ARE system could protect...

Published: 1/14/2025 | Inventor(s): Longqin Hu, Ahmed Ali

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Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Cancer

Fluorogenic bioconjugation of cyclopropanol-containing fluorophores for biological applications

Reference #: 1742 The University of South Carolina is offering licensing opportunities for Fluorogenic bioconjugation of cyclopropanol-containing fluorophores for biological applications. Background: Fluorophores have been used in various applications of cellular microbiology, most notably with the reporting functions associated with various biological...

Published: 1/13/2025 | Inventor(s): Qian Wang, Shan Hu

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Category(s): Chemistry and Biochemistry

Random and Safe (RaS) Cache Architecture to Defeat Cache Timing Attacks

Random and Safe (RaS) Cache Architecture to Defeat Cache Timing Attacks Princeton Docket # 25-4192-1 Princeton University researchers have developed an innovative hardware solution known as Random and Safe (RaS) caches to address critical security vulnerabilities in modern computer systems. This technology significantly enhances security by effectively...

Published: 12/11/2024 | Inventor(s): Ruby Lee, Guangyuan Hu

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Category(s): Mechanical/Electrical Engineering

Rare-Earth-Element Free Yellow Phosphors for White Light-Emitting Diodes

Yellow phosphor emits white light when excited with the 460 nm blue lighting. The blue LED (left half; top) when coated with dispersed yellow phosphor (right half; top) emits white light. Invention Summary: Despite their low energy consumption and higher efficiency, white light-emitting diodes made of blue chip coupled with yellow phosphor...

Published: 12/4/2024 | Inventor(s): Jing Li, Zhichao Hu, Qihan Gong

Keywords(s): Electronics, LEDs

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Electronics/Semiconductor

Novel cermet composite for nuclear waste immobilization

1.5-inch diameter cermet synthesized using hot uniaxial sintering Invention Summary: Nuclear power generates ~10% of electricity globally and ~20% in developed economies. High-level waste, expected to be produced at the back end of advanced reactor fuel cycles, includes metals, oxides, halide salts, and carbon/graphite...

Published: 10/9/2024 | Inventor(s): Ashutosh Goel, John Vienna, John McCloy, S Sundaram, Aditya Kumar, Hans-Conrad zur Loye, Jake Amoroso

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Category(s): Technology Classifications > Energy & Battery, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials

Comprehensive and Individualized Menopause Care Delivery Protocol With Technological Decision Support Aid (Case No. 2024-193)

Summary: Researchers in the UCLA Department of Obstetrics and Gynecology have developed a new clinical decision support system for improved menopause care. Background: Each year, approximately 1.3 million women in the United States enter menopause. This is often accompanied by symptoms such as hot flashes, mood changes, and sleep issues. In addition,...

Published: 2/14/2025 | Inventor(s): Rajita Patil, Erica Oberman, Brittany Davis, Rhonda Voskuhl, Kathleen Van Dyk, Ravi Aysola, Louise Dixon De Silva, Karol Watson, Lua Jafari, Julie Bernthal, Rashmi Mullur, Albert Shieh, Elizabeth Ko, Katie Hu, Aashini Master, Kelly Mccann, Kelsey Collins, Katherine Unverferth, Tamara Grisales, Amy Rosenman, Andrea Rapkin

Keywords(s): clinical care methodology, clinical decision support, EHR, EHR integration, electronic health records (EHR), FemTech, femtech medical device, lab results analysis, medical bias reduction, Menopause, menopause management, patient questionnaire, period, personalized medicine, predictive analytics, specialist referral, women’s health

Category(s): Software & Algorithms, Software & Algorithms > Programs, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > FemTech

New Drugs for the Prevention of Kidney Stones

In vivo efficacy study of an LH prodrug expressed as days CaOx crystals were detected in mouse urine/mouse/week Invention Summary: Hyperoxaluria is a condition characterized by excessive urinary excretion of oxalate. It can result from inherited genetic mutations, intestinal diseases, or a diet high in oxalate. This often leads to calcium...

Published: 11/20/2024 | Inventor(s): Longqin Hu, Yiling Wang

Keywords(s): Drug Discovery/Screening

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

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