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MPL Protein Targeting for Cancer Therapy and Transplant Preparation
Application Non-genotoxic hematopoietic stem cell transplantation conditioning regimen. Key Benefits Selective depletion of hematopoietic stem cells creates adequate niche space to allow donor engraftment without significant off target effect. Non-genotoxic conditioning regimen. CAR-T cells can have an anti-MPL positive leukemia effect before...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s): Shanmuganathan (Shan) Chandrakasan, H. (Harold) Trent Spencer, Christopher Doering, Lauren Fleischer, Gianna Branella, Jaquelyn Zoine, Harrison Brown
Keywords(s): Antibodies, Cell Therapy, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics