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Search Results - surya+pravo+mookherjee
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Irreversible DGKα inhibitors for enhanced T‑cell activation in cancer immunotherapy
Background Cancer immunotherapy seeks to harness the immune system to target and eliminate malignant cells. However, immune suppression within the tumor microenvironment poses a major challenge, blunting T-cell activation and allowing cancer cells to evade immune detection. Diacylglycerol Kinase α (DGKα) is a key enzyme that suppresses...
Published: 7/31/2025
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Inventor(s):
Ku-Lung Hsu
,
Minhaj Shaikh
,
Adam Libby
,
Surya Pravo Mookherjee
Keywords(s):
Category(s):
Life sciences > Therapeutics > Formulation