Search Results - eye

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Surgical Tool for Sub-retinal Tissue Implantation
Abstract: The accurate placement of transplanted tissue at a precise position in the retina is difficult but critical for a successful implementation of an ocular surgical intervention. Researchers at the National Eye Institute (NEI) developed a surgical tool (see image below) designed to place tissue patches, such as sheets of tissue, onto the retina...
Published: 12/6/2024   |   Inventor(s): Arvydas Maminishkis
Keywords(s): EYE, Intra-Ocular, Maminishkis, National Eye Institute, NEI, sub-retinal, surgical tool, tissue placement retina
Category(s): Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology
Methods and Compositions for Treating Genetically Linked Diseases of the Eye
Abstract: X-linked retinoschisis (XLRS) is an inherited, monogenetic ocular disease caused by mutations in the retinoschisin (RS1) gene, resulting in the development of cystic cavities throughout the retina and leading to juvenile macular degeneration. Approximately 1:15,000 males in the US are affected, classifying the condition as an orphan indication.  The...
Published: 12/6/2024   |   Inventor(s): Paul Sieving, Ronald Bush, Yong Zeng, Peter Colosi
Keywords(s): Clinical, EYE, GENE THERAPY, ophthalmological, Orphan Indication, Sieving, XLRS
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology
Ex-vivo Production of Regulatory B-Cells for Use in Auto-immune Diseases
Abstract: Regulatory B-cells (Breg) play an important role in reducing autoimmunity and reduced levels of these cells are implicated in etiology of several auto-inflammatory diseases. Despite their impact in many diseases, their physiological inducers are unknown.  Given that Bregs are a very rare B-cell, identifying factors that promote their development...
Published: 8/14/2024   |   Inventor(s): Charles Egwuagu, Ren-Wi Wang, Chengrong Yu
Keywords(s): ARTHRITIS, B-CELL, COLITIS, EYE, Multiple sclerosis, sarcoidosis
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology