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Search Results - emily+laura+han
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Overcoming the Blood-Brain Barrier with Peptide-Functionalized Lipid Panoparticles
Peptide-functionalized lipid nanoparticles (pLNPs) for targeted messenger RNA (mRNA) delivery to the brain. Problem: Ionizable lipid nanoparticles (LNPs) have emerged as clinically advanced delivery vehicles for nucleic acids. However, as LNPs typically accumulate to the liver, tissue-specific delivery remains challenging, and systemic LNP delivery...
Published: 12/19/2024
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Inventor(s):
Michael Mitchell
,
Emily Laura Han
Keywords(s):
Bioengineering
,
Drug Delivery
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Therapeutics