Search Results - elizabeth+driebe

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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Assay for Detecting and Quantifying Coccidioides
Researchers at TGen and Northern Arizona University (NAU) have developed a real-time qPCR assay for detecting and quantifying Coccidioides immitis and Coccidioides posadasii. The highly sensitive and specific assay can be used by clinicians in rapidly diagnosing Coccidioidomycosis. This assay can be particularly useful outside of the endemic regions...
Published: 11/3/2025   |   Inventor(s): Paul Keim, David Engelthaler, Elizabeth Driebe
Keywords(s):  
Category(s): Diagnostics, Environment
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Methods of Detecting Antiviral Drug Resistant H1N1 Influenza Variants
Researchers at TGen and Northern Arizona University (NAU) have developed a real-time PCR assay for detecting H1N1 influenza strains (which may also be known as as "novel H1N1," "swine flu," and "Mexican flu," among others) in a sample and informing clinicians whether the detected strain is a variant resistant to antiviral...
Published: 11/3/2025   |   Inventor(s): Paul Keim, David Engelthaler, Elizabeth Driebe
Keywords(s):  
Category(s): Diagnostics
Methods of Quantifying Antiviral Drug Resistant Mutations in Influenza A
Researchers at TGen and Northern Arizona University (NAU) have developed a real-time allele specific mixture analysis (ASMA) qPCR assay for quantitatively analyzing the amount of antiviral drug resistant Influenza A mutants in a mixed viral sample. This highly sensitive method provides a cost effective tool for clinical or public health laboratories...
Published: 11/3/2025   |   Inventor(s): Paul Keim, Elizabeth Driebe, David Engelthaler, Cindy Liu
Keywords(s):  
Category(s): Diagnostics
Allelic Discrimination Assays for MRSA Strains
Researchers at TGen and Northern Arizona University (NAU) have developed methods to rapidly identify and differentiate Methicillin-Resistant Staphylococcus aureus (MRSA) strains using real-time PCR assays. These allelic discrimination assays target SNPs to distinguish the clinically important MRSA strains USA100, USA300, USA 600, and other MRSA strains,...
Published: 11/3/2025   |   Inventor(s): Paul Keim, Elizabeth Driebe, David Engelthaler, Jolene Bowers
Keywords(s):  
Category(s): Diagnostics
Assays for Antibiotic Resistance Gene Detection in Staphylococcus Strains
Researchers at TGen and Northern Arizona University (NAU) have developed a multiplex real-time PCR profiling assay for detecting antibiotic resistance-conferring genes in Staphylococcus strains. The multiplex assay determines the susceptibility of strains such as MRSA, MSSA, MRSE, and MSSE to antibiotics including aminoglycoside, vancomycin, penicillin,...
Published: 11/3/2025   |   Inventor(s): Paul Keim, Elizabeth Driebe, David Engelthaler, Jolene Bowers
Keywords(s):  
Category(s): Diagnostics
MAMA Real-Time PCR Assay Panel for Genotyping Cyrptococcus gattii
Researchers at TGen and Northern Arizona University (NAU) have developed methods for genotyping Cryptococcus gattii using a mismatch amplification mutation assay (MAMA) real-time PCR assay panel. This assay panel provides a rapid method for genotyping of C. gattii molecular types VGI-VGIV and the dominate North American VGII molecular subtypes VGIIa-c...
Published: 11/18/2025   |   Inventor(s): David Engelthaler, Elizabeth Driebe, Erin Kelley, Paul Keim
Keywords(s): Pathogens
Category(s): Genomics/Genetics, Diagnostics
Repurposed Drugs for the Treatment of Fungal Infections Caused by Coccidioides
Researchers at TGen and Northern Arizona University (NAU) have developed an effective treatment for fungal infections caused by Coccidioides including the Valley Fever-causing species: Coccidioides immitis and Coccidioides posadasii in humans and companion animals (particularly canines). Repurposed drugs originally developed to inhibit hormone uptake...
Published: 11/3/2025   |   Inventor(s): David Engelthaler, Elizabeth Driebe, Hongwei "Holly" Yin, Michael Valentine, Donald Chow, Jolene Bowers, Paul Keim
Keywords(s): Animal Health, Pathogens, Veterinary Medicine
Category(s): Therapeutics
Amplicon Sequencing Analysis Pipeline (ASAP)
TGen and Northern Arizona University have developed a high-throughput bioinformatics tool for interpreting the significance of alignment data from amplicon sequencing. Amplicon sequencing allows for rapid, cost-effective, highly multiplexed, and accurate detection of numerous clinically important targets directly in clinical samples. The Amplicon...
Published: 11/18/2025   |   Inventor(s): Darrin Lemmer, Jolene Bowers, Elizabeth Driebe, Erin Kelley, David Engelthaler, Paul Keim
Keywords(s):  
Category(s): Computer Methods, Diagnostics
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