Search Results - dna+checkpoint

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A Rabbit Anti-pT1989 ATR Monoclonal Antibody for Use in Immunoassays
Abstract: Ataxia telangiectasia mutated and Rad3 Related (ATR) protein kinase is essential for regulating DNA damage checkpoints during the cell cycle. ATR, is phosphorylated at threonine 1989 site (T1989) in response to DNA damage and ATR activation leads to activation of downstream substrates, signaling cascades and cell cycle arrest. ATR is a potential...
Published: 4/8/2024   |   Inventor(s): Thomas Pfister, Allison Marrero, Ralph Parchment, James Doroshow, Robert Kinders
Keywords(s): ANTIBODY, assay, Ataxia telangiectasia mutated and Rad3-related kinase, CANCER, diagnostic, DNA checkpoint, monoclonal
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics