Search Results - danny+bluestein

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Polymeric Valve for Tricuspid Applications

This invention is a medical implant that is made of polymeric and metallic materials that functions as a replacement valve for tricuspid applications. The valve functions as a flow regulator and can be installed in low pressure, low flow, and low shear cardiovascular structures. It is specifically engineered to reduce stress on the implant structure...

Published: 1/16/2024 | Inventor(s): Marvin Slepian, Danny Bluestein, Brandon Kovarovic

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Medical Devices > Therapeutic

y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability

Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...

Published: 9/25/2023 | Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA

Keywords(s): Drug Discovery, Immunology

Category(s): Technology Classifications > Medical > Biotechnology

Heart Valve for Eccentric Orifice

This technology is a novel heart valve and deployment system that maintains eccentric geometries while optimizing valve function and hemodynamics, reducing adverse events. The asymmetrical leaflet design features two identical mirrored larger leaflets and one shorter leaflet. Traditional symmetric leaflet design features three equal leaflets that rely...

Published: 11/16/2023 | Inventor(s): Marvin Slepian, Danny Bluestein, Brandon Kovarovic, Ryan Helbock

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Therapeutic, Technology Classifications > Healthcare Portfolios > Heart and Vascular

Polymeric Heart Valve System and Method of Manufacture

This invention is a new polymer-based heart valve designed to reduce stress on the leaflets of the valve while in use in the human body, providing for longer-term durability compared to other polymer-based valves. Background: According to the CDC, heart disease is the leading cause of death in the United States: about one in every four deaths is due...

Published: 11/16/2023 | Inventor(s): Marvin Slepian, Danny Bluestein, Oren Rotman, Brandon Kovarovic

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Medical Devices

Nature-inspired Functionally-graded UHMWPE + Kevlar Composites Achieve Extraordinarily High Strength

Nature-inspired polymers are achieved using unique processing to yield functional gradient composites with embedded Kevlar fibers exhibiting extraordinarily high strength lightweight UHMWPE materials. Background: Demand for new energy absorption materials and implantable polymeric biomaterials has increased significantly in recent years. The...

Published: 7/9/2024 | Inventor(s): Shenqiang Ren, Lu An

Keywords(s): Technologies

Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Technology Classifications > Engineering

Biomarker Signatures of Platelet Activation

This invention is a mechanical biomarker signature of shear effects on cells for the purpose of detecting thrombosis early so it can be treated or intercepted prior to a thrombotic event. Background: Thrombosis is a pathophysiological event that can trigger conditions like stroke or heart attack. The efficacy of many antithrombotic agents is shear...

Published: 2/9/2024 | Inventor(s): Marvin Slepian, Yana Roka Moiia, Danny Bluestein, Naing Bajaj, Michael Dicaro, Louise Hecker

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Oncology

Network-Coded Multiple Access

[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...

Published: 1/29/2024 | Inventor(s): Soung Chang Liew, Lu LU, Lizhao You

Keywords(s): Network Coding, Wireless Local Area Network

Category(s): Information and Communications Technology

HyperShear in a Channel: A Microfluidic Facsimile of Ventricular Assist Devices to Reduce Thrombotic Risk and Enhance Patient Safety

This technology utilizes device thrombogenicity emulation--a method which mimics the shear stresses that would be exhibited within the patient in order to assess proper anti-thrombolytic therapies. Shear stresses are observed in a microfluidic facsimile of a ventricular assist device (VAD), which can quickly be translated to assess the personal risk...

Published: 11/16/2023 | Inventor(s): Marvin Slepian, Alberto Redaelli, Danny Bluestein, Marco Rasponi

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic