Search Results - louise+hecker

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Repurposing an FDA-Approved Drug for Treating Age-Associated Lung Fibrosis
Application New use of an FDA-approved therapeutic, diroximel fumarate (Vumerity), for treating Idiopathic Pulmonary Fibrosis. Key Benefits Novel use of an FDA-approved drug, diroximel fumarate - DRF (Vumerity), for treating age-dependent lung fibrosis. Lung-targeted inhaled delivery of DRF is effective for boosting lung antioxidant responses...
Published: 8/22/2024   |   Inventor(s): Louise Hecker, Kosuke Kato
Keywords(s): Repurposed Drug, Respiratory
Category(s): TechPub Algolia > Therapeutics
Therapeutic to Treat Age-Dependent Idiopathic Pulmonary Fibrosis
Application Therapeutic for treating age-associated lung fibrosis. Key Benefits Tecfidera (dimethyl fumarate - DMF) is an FDA approved therapy to treat multiple sclerosis via oral administration. A novel formulation for inhaled delivery demonstrated efficacy for a new indication: Idiopathic Pulmonary Fibrosis (IPF), where it promotes the reversal...
Published: 8/22/2024   |   Inventor(s): Louise Hecker, Kosuke Kato, Priyadarshini Muralidharan, Heidi Mansour
Keywords(s): Repurposed Drug, Respiratory
Category(s): TechPub Algolia > Therapeutics
Biomarker Signatures of Platelet Activation
This invention is a mechanical biomarker signature of shear effects on cells for the purpose of detecting thrombosis early so it can be treated or intercepted prior to a thrombotic event. Background: Thrombosis is a pathophysiological event that can trigger conditions like stroke or heart attack. The efficacy of many antithrombotic agents is shear...
Published: 2/9/2024   |   Inventor(s): Marvin Slepian, Yana Roka Moiia, Danny Bluestein, Naing Bajaj, Michael Dicaro, Louise Hecker
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Oncology
Reactive Oxygen Species Gene Signature Predicts Survival in Sepsis
This technology is a 21-gene reactive oxygen species (ROS)-associated molecular signature that predicts survival in septic patients. This particular signature has outperformed randomly generated signatures of the same signature gene size. This signature is easily assayed from peripheral blood and can potentially predict. Background: There is a significant...
Published: 11/16/2023   |   Inventor(s): Louise Hecker, Marvin Slepian, Christian Bime, Tong Zhou, Nima Pouladi, Ting Wang
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics