Search Results - changyu+zheng

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Thermal Control During Additive Manufacturing
THE CHALLENGE Additive manufacturing (AM) has emerged as a powerful tool within engineering. Many AM and coating processes rely on thermal input to soften or melt the materials involved in processing. However, this melting or softening typically results in a higher thermal gradient between deposited material and the workpiece, commonly resulting in...
Published: 12/20/2023   |   Inventor(s): Robert Griffiths, David Garcia, Hang Yu
Keywords(s):  
Category(s): EXPERIMENT--DO NOT USE, Technology Classifications > Additive Manufacturing
Hybrid Adeno-Retroviral Vector for the Transformation of Cells (E-258-1998)
The invention described and claimed in this patent application provides for novel hybrid vectors which may be used for cell transformation, either in vivo or in vitro. The hybrid vectors have an adenoviral backbone with retroviral long terminal repeats (LTRs). Such vectors are capable of transforming dividing or non-dividing cells and integrate stably...
Published: 7/25/2024   |   Inventor(s): Bruce Baum, Brian O'connell, Changyu Zheng
Keywords(s): Adeno-Retroviral, Chimeric Vector, Duke DNA Project, GB2A2X, GB2AXX, GB2XXX, GBXXXX, GENE THERAPY, GXXXXX, hybrid vector, Vector, viral vector
Category(s): Application > Therapeutics
Hybrid Adeno-Retroviral Vector for the Transformation of Cells (E-312-2000)
The invention described and claimed in these patent applications provides for novel hybrid vectors which may be used for cell transformation either in vivo, in vitro, or ex vivo. The hybrid vectors, which are capable of integrating into the chromosome of the host cell and are capable of transducing dividing and non-dividing cells, have an adenoviral...
Published: 7/25/2024   |   Inventor(s): Changyu Zheng, Brian O'connell, Bruce Baum
Keywords(s): GB2AXX, GB2CXX, GBXXXX, GXXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 4/19/2023   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging