Search Results - cb1

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Small Interfering RNA Inhibition of Cannabanoid-1 Receptor (CB1R) for Treating Type 2 Diabetes
The invention pertains to the use of glucan encapsulated non-immunostimulatory small interfering RNAs (siRNAs) to treat type-2 diabetes. Endocannabinoids (EC) are lipid signaling molecules that act on the same cannabinoid receptors that recognize and mediate the effects of endo- and phytocannabanoids. EC receptor CB1R activation is implicated in the...
Published: 10/28/2024   |   Inventor(s): Tony Jourdan, Michael Czech, Myriam Aouadi, George Kunos
Keywords(s): CB1, DIABETES, GB1AXX, GB1XXX, GBXXXX, GXXXXX, IBXXXX, IXXXXX, Knockdown, MACROPHAGES, RECEPTORS, SELECTIVE, SiRNA-mediated, treatment
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics
Immune CB1 Activation for Obesity Therapy
Reference #: 01478 The University of South Carolina is offering licensing opportunities for Immune CB1 activation for obesity therapy Background: The endocannabinoid system regulates various physiological processes such as inflammation and metabolism, and is comprised of cannabinoid receptors, CB1 and CB2, as well as their ligands called endocannabinoids....
Published: 5/22/2024   |   Inventor(s): Prakash Nagarkatti, Mitzi Nagarkatti, Kathryn Miranda
Keywords(s): anti-inflammatory pharma, cannabinoids, CB1, inflammation, metabolic syndrome, Obesity, weight loss
Category(s): Health Sciences, Biomedical and Life Sciences