Search Results - binwu+tang

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Reporter Plasmid to Identify Cancer Stem Cells
Abstract: Cancer stem cells are a minority population of cells in tumors that initiate and sustain the cancer and which are resistant to therapy; they may cause tumors to recur after curative treatment.  Current therapies generally do not target cancer stem cells. Scientists at the National Cancer Institute Laboratory of Cancer Biology and Genetics...
Published: 5/23/2024   |   Inventor(s): Lalage Wakefield, Binwu Tang
Keywords(s): Lentiviral, Oct4, PLASMID, reporter construct, Sox2
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials
SARS-COV-2 papain-like protease inhibitors as antivirals
Novel compounds and their use as an inhibitor for SARS-CoV-2. Invention Summary: Two oral SARS-CoV-2 antivirals are available, molnupiravir and Paxlovid. However, the limited efficacy, drug-drug interaction, and drug resistance are main challenges facing these two drugs. Additional oral antivirals with novel mechanisms of actions are clearly needed....
Published: 8/20/2024   |   Inventor(s): Jun Wang, Edward Arnold, Francesc Ruiz Figueras, Prakash Jadhav, Bin Tan, Ahmadullah Ansari, Ashima Chopra
Keywords(s): Antiviral, Small molecules
Category(s): Technology Classifications > COVID-19, Technology Classifications > Infectious Disease, Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences
Tunable Degradation of Fibers
­ Executive Summary Degradation of polymeric materials is an important process in recycling, composting and rendering them innocuous to the environment. Controlling the rate by which the materials degrade remains challenging and impacted by the nature of the materials and their use in applications where combinations of materials exist to fulfil...
Published: 2/17/2023   |   Inventor(s): John Dorgan, Bin Tan
Keywords(s):  
Category(s): Advanced Materials, Environment, Packaging