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Search Results - analgesic
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ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR AND CANNABINOID RECEPTOR 1
ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR AND CANNABINOID RECEPTOR 1 Researchers at Stanford have synthesized a potential novel class of pain relief drugs. Traditional opioids, while highly effective for acute pain management, have historically been prescribed as long-term
analgesic
treatments despite their well-known addictive properties....
Published: 9/14/2023
|
Inventor(s):
Evan Obrien
,
Brian Kobilka
,
Krishna Kumar
Keywords(s):
Analgesic
,
Opiod
,
Pain
Category(s):
Technology Classifications > Chemistry
Slc5a7 (choline transporter, CHT) BAC Transgenic Mouse
A Bacterial Artificial Chromosome (BAC) containing the mouse Slc5a7 gene was used to make transgenic mice. Mice show elevated choline transporter and acetylcholine levels and increased treadmill endurance. These mice permit the study of elevated presynaptic choline transporter protein in vivo, expressed solely in cholinergic neurons due to the BAC...
Published: 4/18/2016
|
Inventor(s):
Keywords(s):
Analgesic
,
Cardiovascular
,
Inflammatory/Immune
,
Metabolic Disorders/ Diabetes
,
Neuroscience/Neurology
Category(s):
Research Tools
Small molecule-GIRK Potassium Channel Modulators are Anxiolytic Therapeutics
Summary The G-protein activated, inward-rectifying potassium (K+) channels, “GIRKs”, are a family of ion channels that has been the focus of intense research interest for nearly two decades. GIRK has been shown to play important roles in the pathophysiology of diseases such as anxiety, epilepsy, Down’s syndrome, pain perception and...
Published: 6/21/2024
|
Inventor(s):
Charles Weaver
,
P. Jeffrey Conn
Keywords(s):
Analgesic
Category(s):
Therapeutics