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Engineered antibodies for enhanced immune response
Recombinant antibodies with engineered human IgG1 Fc domains have been developed to resist viral Fc receptor capture, enhancing immune targeting of virus-infected cells. These antibodies maintain normal host receptor affinity, potentially improving therapeutic outcomes against HCMV and related viruses. Background Human cytomegalovirus (HCMV) infection...
Published: 8/28/2025   |   Inventor(s): Jennifer Maynard, Ahlam Qerqez, Alison Lee, Sumit Pareek
Keywords(s):  
Category(s): Life sciences > Immunology