Silicon Carbide Nanoparticles Fibrous Membrane for Implantable Glucose Sensors

Advantages

  • Easy to fabricate, cost-effective, energy-efficient, and adaptable for detecting diverse biochemical reactions through suitable material choice and surface functionalization.
  • Delivers low-noise, high-gain, linear, and stable performance at significantly lower power than previous state-of-the-art potentiostats.
  • High sensor durability with 11% performance change sustained over 50 days.
  • Highly sensitive, capable of measuring electrochemical currents from 2 µA to 200 µA, with a sensitivity of 30.75 µA/mM·cm² and a low detection limit of 0.56 µM glucose.

Summary

Glucose sensors are used to measure the glucose concentration of a blood in a patient and are an important part of managing diabetes mellitus. This continuous glucose monitoring system needs to be power efficient, compact, portable, sensitive, and have a linear response for targeted levels. This method represents an integrated system with a CMOS based low-power, low-noise chronoamperometric potentiostat circuit and SiCNPs-ENFM based glucose sensor on a single chip. The sensing unit can detect micro amps of electrochemical current from the SiCNPs-ENFM glucose sensor with better sensitivity, limit of detection, fast response time and durability, providing the base for future wearable and portable biosensors.

Block diagramof SiCNPs-ENFM based glucose sensor with the integration of chronoamperometric potentiostat.

Desired Partnerships

  • License
  • Sponsored Research
  • Co-Development
Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date
SILICON CARBIDE NANOPARTICLES FIBROUS MEMBRANE FOR IMPLANTABLE GLUCOSE SENSOR INTEGRATED WITH CHRONOAMPEROMETRIC POTENTIOSTAT Utility United States 17/335,276 12,453,496 6/1/2021 10/28/2025 6/1/2041