High-throughput drug discovery and cell-based screening are often limited by costly cleanroom fabrication, permanent bonding methods, and unreliable sealing that leads to leakage and contamination. Many microfluidic platforms are difficult to sterilize or reuse, increasing operational costs and limiting scalability for research labs and translational applications.
This technology introduces a five-layer SLA 3D printed microfluidic chip secured within a custom compression bracket that prevents fastener-induced leaks. A reversible gasket-based sealing system enables repeated sterilization and reuse. Standard luer-lock interfaces support secure fluid connections, creating a practical, scalable platform for droplet-based cell encapsulation and screening workflows.
Microfluidic pump box with integrated chip holder, tubing connections, and user control interface.