After lung cancer surgery, patients often still face high risks of recurrence because traditional chemotherapy circulates throughout the entire body, causing severe side effects while delivering only a limited amount of drug to the tumor site. Current delivery methods struggle to maintain effective drug levels where they are needed most, leading to reduced treatment impact and added patient burden.
This technology introduces a localized drug-delivery membrane that releases cancer therapeutics directly into the surgical site over an extended period. The membrane combines biodegradable materials with embedded nanoparticles to provide targeted, sustained treatment while minimizing systemic exposure. This approach enhances therapeutic effectiveness, reduces side effects, and offers a scalable platform for post-surgical cancer care.
This figure shows the electrospinning setup showing how a high-voltage electric field draws a polymeric solution into fine nanofibers, which solidify into a mesh on the collector plate for use in multilayer drug-delivery membranes.