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Biocompatible photoenzymatic system for selective C–H fluorination

Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....

Published: 7/31/2025 | Inventor(s): Yi Lu, Yu Zhou

Keywords(s):

Category(s): Life sciences > Metabolic engineering

A General Cation-Exchange Approach to Magnetic Intercalation Superlattices (Case No. 2025-9A1)

Summary: UCLA researchers in the Department of Chemistry have developed a general cation-exchange approach for tunable magnetic intercalation superlattices. Background: Layered materials are crucial for engineering quantum and magnetic phenomena at the atomic scale. Magnetic intercalation superlattices, a type of layered materials, enable tunable...

Published: 7/24/2025 | Inventor(s): Xiangfeng Duan, Yu Huang, Jingxuan Zhou

Keywords(s): Advanced Computing / AI, advanced packaging, Cation exchange, doping control, Fabrication Technologies, ferromagnetic semiconductor, layered materials, magnetic coupling, magnetic intercalation superlattices, quantum communication, Quantum Computer, quantum computing materials, Quantum Dot, quantum error correction (QEC), quantum incompressible fluid, quantum key, quantum network, quantum processing, quantum processor, room-temperature superconductivity, spin textures, spintronics, trapped ion quantum processor, tunable ferromagnetism, Van der Waals, Van Der Waals Force, VIN group metals

Category(s): Materials, Materials > Nanotechnology, Materials > Functional Materials, Materials > Semiconducting Materials, Materials > Fabrication Technologies, Materials > Metals, Optics & Photonics

Exceptional Point Optomechanical Infrared Thermal Imaging Detector (EPOPTIM)

Background Mid to long-wave infrared detectors capture and interpret infrared radiation emitted by objects, and convert it into additional data. These detectors have wide ranging applications including gas sensing, thermal imaging, environmental monitoring, and defense applications. Typically, these detectors use micro- or nano-scale microwave-frequency...

Published: 7/24/2025 | Inventor(s): Yu Yao, Linbo Shao, Yizheng Zhu

Keywords(s):

Category(s): Physical Science, Imaging, Environmental, Applied Technologies

Integrated Sensing and Communication System Using Backscattering RFID Tags

Background Integrated sensing and communication (ISAC) has been envisioned to benefit various emerging applications in the future, with enhanced spectral, energy, and hardware efficiency. One potential scenario is the use of radio frequency identification (RFID) for inventory management in warehouses or retail stores, where low-cost passive RFID tags...

Published: 7/14/2025 | Inventor(s): Ahmed Alkhateeb, Hao Luo, Umut Demirhan

Keywords(s):

Category(s): Physical Science, Wireless & Networking, Energy & Power, Applied Technologies

Surface Oxophilic Single Atom Decoration of PT Catalyst for Anion Exchange Membrane Fuel Cells (Case No. 2025-263)

Summary: Researchers at UCLA's Department of Chemistry and Biochemistry have developed a novel catalyst design using oxophilic single-atom decorations that enhances the performance and durability of platinum (Pt) catalysts in alkaline exchange membrane fuel cells. Background: Hydrogen fuel cells are a promising alternative to internal combustion...

Published: 6/24/2025 | Inventor(s): Xiangfeng Duan, Yu Huang, Chengzhang Wan

Keywords(s): anion exchange membrane fuel cells (AEMFCs), Catalysts, catalytic hydrogenation, clean energy, clean energy consumption, clean material production, Composite Material, Composite Materials, Construction Materials, Electrocatalyst, electrochemically active surface area, high-durability catalysts, Hydrogen, Hydrogen oxidation reaction, hydrogen oxidation reaction (HOR), hydrogen production, low overpotential catalysis, mass activity, material science, Materials, meta materials, Methane Reformer Hydrogen Production, microarchitectured materials, Nanomaterials, nanostructured materials, Nanotechnology, oxygen oxidation reaction, oxygen reduction reaction (ORR), Platinum group metal catalysts, proton exchange membrane fuel cells (PEMFCs), proton exchange water membrane electrolyzer (PEMWE), Rhodium-decorated Platinum nanowires (SARh-PtNW), specific activity, transition metal catalysts

Category(s): Materials, Materials > Nanotechnology, Materials > Functional Materials, Energy & Environment, Energy & Environment > Energy Generation, Energy & Environment > Energy Efficiency, Energy & Environment > Energy Transmission, Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Synthesis, Chemical > Catalysts

Multi-Object Grasping -- Grasping from Surface of Pile

Advantages: High Efficiency in Cluttered Environments Vision-Guided Dexterity with 6D Pose Estimation Confidence-Driven Grasp Optimization Adaptive to Real-World Variability Scalable for Industrial Automation Summary: Robotic grasping in industries like manufacturing, warehousing, and logistics is still a bottleneck when dealing with dense...

Published: 5/28/2025 | Inventor(s): Tianze Chen, Yu Sun

Keywords(s): Robotics

Category(s): Technology Classifications > Engineering > Chemical Engineering, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Engineering > Industrial Engineering

High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases

Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...

Published: 5/27/2025 | Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An

Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment

Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals

Multi-material electrospinning system for 3D-printed fiber architectures

Background Electrospinning and additive manufacturing have become increasingly important in fields such as biotechnology, pharmaceuticals, and tissue engineering, where there is growing demand for complex fiber architectures and multifunctional material systems. However, traditional electrospinning methods struggle to meet the precision, scalability,...

Published: 4/25/2025 | Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi, Ishaan Duggal

Keywords(s):

Category(s): Life sciences > Therapeutics > Manufacturing platform

VITRUALGENOME, A VIRTUAL REALITY IMMERSIVE SYSTEM

VAlue proposition A virtual reality immersive system that enables users to visualize, explore, and analyze 3D genomes and their associated biochemical features. Combining VirtualGenome with Tensor-FLAMINGO and 3DVarientVision creates a technology that provides a high-resolution image of the altered 3D structure resulting from a genetic variant, decodes...

Published: 4/9/2025 | Inventor(s): Jianrong Wang, Andre Popovitch, Hao Wang

Keywords(s):

Category(s): Biotechnology, Computer Software, Education & Training

HIGH-RESOLUTION RECONSTRUCTION OF SINGLE-CELL 3D CHROMOSOMAL STRUCTURES

VAlue proposition The dynamic 3D spatial structure of chromosomes has variations across cells of different types and between cells of the same type. This structural variation between single cells plays an important role in regulating single-cell specific transcription and epigenetic landscapes. Computationally reconstructing chromosomal 3D structure...

Published: 4/9/2025 | Inventor(s): Jianrong Wang, Jianliang Qian, Hao Wang

Keywords(s):

Category(s): Biotechnology, Computer Software

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