Search Results - yiliang+luan

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ARPLA: a revolutionary glycoRNA imaging tool with precision and power
Background/problem Glycosylated RNAs (GlycoRNAs) are a newly discovered class of molecules involved in glycosylation. They have been found on the surfaces of various cell types, organisms, and species, further advancing the role of RNA in biological processes. Despite this, our knowledge of glycoRNAs and their functions remains limited, primarily...
Published: 7/26/2024   |   Inventor(s): Yi Lu, Yuan Ma, Weijie Guo, Quanbing Mou
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
Potent And-1 Inhibitors that Suppress Tumor Growth and Overcome Platinum Drug Resistance
­Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women. The survival rate of ovarian cancer patients is low largely due to platinum-based chemotherapy resistance and lack of alternative regimens. Recent studies showed that the Acidic nucleoplasmic DNA-binding protein 1 (And-1) activation promotes platinum drug resistance...
Published: 7/30/2024   |   Inventor(s): Wenge Zhu, Yiliang Li, Jing Li
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules
SENP1 Enzymatic Activity Inhibitors for Platinum Resistant Ovarian Cancer
­Ovarian cancer is one of the leading causes of cancer-related deaths in women. The survival rate of ovarian cancer patients is low largely due to platinum-based chemotherapy resistance and lack of alternative regimens. A recent study indicated that Janus tyrosine kinase 2 (JAK2), which activates the signal transducers and activators of transcription...
Published: 7/30/2024   |   Inventor(s): Wenge Zhu, Jing Li, Ruiqin Wu, Yiliang Li
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Nature-inspired Functionally-graded UHMWPE + Kevlar Composites Achieve Extraordinarily High Strength
Nature-inspired polymers are achieved using unique processing to yield functional gradient composites with embedded Kevlar fibers exhibiting extraordinarily high strength lightweight UHMWPE materials. Background: Demand for new energy absorption materials and implantable polymeric biomaterials has increased significantly in recent years. The...
Published: 7/9/2024   |   Inventor(s): Shenqiang Ren, Lu An
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Technology Classifications > Engineering
High-Throughput Microfluidic Instrument for Constructing Custom Synthetic Vesicles with Asymmetric Membranes
Microfluidic device for constructing custom synthetic vesicles with controlled asymmetry Background: The ability to fabricate complex model membrane systems that are physiologically relevant to their natural systems has been a challenge in past decades. Conventional methods such as electroformation, gel hydration, bulk inverted emulsion, extrusion,...
Published: 12/28/2023   |   Inventor(s): Li Lu, Sepehr Maktabi, Paul Chiarot, Jeffrey Schertzer
Keywords(s):  
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University
A Novel and Robust Method to Yield Stable, Highly Active and Mass-Producible Pt3Ni Catalysts
Novel method for facile development of high-performance nanoframe catalysts using size and crystallographic face-controlled PtNi4 tetrahexahedral nanocrystals prepared through a colloidal synthesis as precursors Background: Pt-based nanoframes are a new class of nanomaterials that have great potential as high performance catalysts. However, their...
Published: 5/18/2022   |   Inventor(s): Jiye Fang, Yiliang Luan
Keywords(s): #SUNYresearch, CleanTech, Technologies
Category(s): Technology Classifications > Nanotechnology, Campus > Binghamton University
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023   |   Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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