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Search Results - yan+jessie+zhang
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Small molecule compounds for REST degradation in glioblastoma cells
Scientists developed a new drug, GR-28, that inhibits a protein called SCP1. This leads to the degradation of another protein, REST, which promotes the growth of brain tumor cells. Combining GR-28 with a lipid metabolism inhibitor shows synergistic effects in killing tumor cells. Background Glioblastoma (GBM) is a highly aggressive and fatal brain...
Published: 10/22/2024
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Inventor(s):
Yan Jessie Zhang
,
Svetlana Panina
,
Dionicio Siegel
Keywords(s):
Category(s):
Life sciences > Therapeutics > Formulation
Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...
Published: 9/26/2024
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Inventor(s):
Li Niu
,
Zhen Huang
,
Yan Han
,
Congzhou Wang
,
Jae Seon Park
Keywords(s):
RNA
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus
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Campus > University at Albany
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
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Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
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Technology Classifications > Imaging & Optics > Medical Imaging
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Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Grouping Algorithm for Touchscreen Finger Position Detection (Case No. 2016-520)
Case 2016-520UCLA researchers in the Department of Electrical Engineering developed a new grouping algorithm for touchscreen finger position detection.BACKGROUNDTouchscreen technology plays an important role in the booming mobile devices market. Conventional touchscreens are designed with both horizontal and vertical electrodes. When these sensors are...
Published: 9/10/2024
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Inventor(s):
Mau-Chung Frank Chang
,
Chunchen Liu
,
Li Du
,
Yan Zhang
Keywords(s):
Software & Algorithms
Category(s):
Software & Algorithms
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Software & Algorithms > Programs
A Pashto-English Dictionary
This technology is a multi-use dictionary that contains Pashto entries with corresponding English words, allowing individuals to learn either Pashto or English. Background: Current versions of online Pashto dictionaries have varying amounts of Pashto entries with English translations, many of which have no verification of their learning materials,...
Published: 4/3/2023
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Inventor(s):
Yan Han
,
Atifa Rawan
Keywords(s):
Category(s):
Technology Classifications > Creative Works
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Technology Classifications > Software & Information Technology > Web & Internet