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Cell Culture Dishes with Dynamically Reconfigurable Surface Textures for Cell Expansion and Harvesting
Advantages Enzyme-free individual cell harvesting: avoids cellular damage, preserving cell viability and surface receptors Single-cell resolution: Releases dispersed individual cells rather than large confluent sheets, which is ideal for clonal assays Rapid (<1 min), mild stimulus-triggered detachment: triggers detachment via a brief temperature...
Published: 7/24/2025   |   Inventor(s): Nathan Gallant, Ryan Toomey, Michael Cross
Keywords(s):  
Category(s): Technology Classifications > Chemistry > Polymers, Technology Classifications > Medical > Biomaterials, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Research Tools/Copyright
A Microfluidic-coupled in vitro Model of the Blood-Brain Barrier (BBB)
Advantages Real-time trans endothelial electrical resistance (TEER) monitoring: embedded Ag/AgCl electrodes enables high-resolution impedance spectroscopy, outperforming conventional models Physiologically relevant tri-culture design: microfluidic flow mimics in vivo BBB hemodynamics with spatially separated HUVECs, astrocytes, and pericytes Enhanced...
Published: 6/5/2025   |   Inventor(s): Shyam Mohapatra, Subhra Mohapatra, Tao Wang, Taylor Martinez
Keywords(s):  
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Cell & Tissue Engineering, Technology Classifications, Technology Classifications > Research Tools/Copyright, Technology Classifications > Medical > Neuroscience
: Mouse Models for Studying Hyperglycemia-induced Hyperfiltration via NOS1 and NKCC2 Proteins (NOS1Cre / NKCC2ftox / NOS1Cre-NKCC2ftox Mice)
Competitive Advantages Future applications for treatment of diabetic nephropathy Three mouse models for utilization in diabetic research Defined mechanism behind glomerular hyperfiltration Summary Abnormal regulation of sodium reabsorption in the thick ascending limb and macula densa underpins disorders such as salt-sensitive hypertension and...
Published: 7/9/2025   |   Inventor(s): Ruisheng Liu
Keywords(s): Diabetes, Laboratory Methods
Category(s): Technology Classifications > Medical, Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Research Tools/Copyright