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3D-Printed Extracellular Vesicles (EVs) for DNA/RNA Sequencing
Enables Single Vesicle DNA/RNA Sequencing to Differentiate Sub-Populations of Extracellular Vesicles (EVs) These 3D-printed extracellular vesicle (EV) droplets enable DNA and RNA sequencing to differentiate extracellular vesicle subpopulations. Extracellular vesicles are nanosized vesicles containing a variety of cargo, including mRNA, proteins, and...
Published: 9/4/2024   |   Inventor(s): Thomas Schmittgen, Thomas Angelini, Andrew Brock, Jinmai Jiang, Senthilkumar Duraivel
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Others, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Diagnostics
Electroencephalography (EEG) Artifact-Removing Algorithm
Uses Reference Noise Recordings to Isolate and Remove EEG-Corrupting Artifacts in Real-Time This algorithm isolates and removes artifacts from electroencephalography (EEG) recordings in real-time, enabling the acquisition of clean data signals. EEG hardware is an essential tool for detecting brain waves in real-world mobile environments with high temporal...
Published: 9/3/2024   |   Inventor(s): Ryan Downey
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Equipment, Technology Classifications > Human Health Care > Diagnostics
Non-Invasive Machine Learning Software for Diagnosing Parkinson's Disease
Uses Blood Vessel Patterns Taken from Retinal Fundus Images to Predict an Onset or Presence of Parkinson’s Disease This non-invasive machine learning software uses fundus retinal images to predict the onset or presence of Parkinson’s disease (PD). Parkinson’s disease is the second most common neurodegenerative disorder, affecting...
Published: 9/3/2024   |   Inventor(s): Ruogu Fang, Maximillian Diaz
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics
High-Yield Synthesis of Glycosphingolipids
Enables Simple and Efficient Synthesis of Various Glycosphingolipids and their Derivatives for Diagnostic and Biological Applications This strategy enables the diversity-oriented synthesis of various glycosphingolipids (GSLs). GSLs are a family of glycolipids with a sphingoid or a ceramide as the hydrophobic moiety linked to the downstream end of a...
Published: 9/3/2024   |   Inventor(s): Zhongwu Guo, Qingjiang Li
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Therapeutics
Rapid Diagnostic Test for Detecting Bacterial Infections
Uses Nucleic Acid Amplification to Accurately Detect Virtually All Bacterial Species in Clinical Samples This rapid PCR-based test uses nucleic acid amplification to quickly and accurately detect harmful bacteria from blood samples without producing false positives. Bloodstream infections (BSI) are among the most severe manifestations of bacterial...
Published: 1/30/2024   |   Inventor(s): Kenneth Rand, Herbert Houck
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Others, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Diagnostics
Mixed-Reality Medical Imaging System for Patient Alignment in Radiation Oncology
Orients and Aligns a Patient with a Medical Device for Optimal and Precise Delivery of Radiation Therapy Safe and effective radiotherapy (RT) requires the reproduction of a specific patient posture and the precise alignment of the patient with an RT device. Any difference in these two aspects can lead to under-dosing the tumor or overdosing healthy...
Published: 2/6/2024   |   Inventor(s): Perry Johnson
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Others
Adaptive Olfactory Measure of Threshold (ArOMa-T) an Olfactory Dysfunction Test
Evaluates an Individual's Sense of Smell Using a Novel Adaptive Algorithm Paired with a Card-Based Tool to Determine Odor Detection Thresholds This odor detection threshold test pairs a novel adaptive algorithm with a card-based tool to rapidly determine an individual’s odor detection threshold. Potential uses include: (1) assessing changes...
Published: 2/27/2024   |   Inventor(s): Steven Munger
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Others
3D Bio-Printed Functional Liver Tissue Model
Predicts Liver Toxicity during the Drug Development Process This 3D bio-printed liver tissue model, which exhibits the functions of a human liver, tests for and predicts the liver toxicity of new drug therapies. Current approaches used in testing the potential liver toxicity in a compound during the drug development process are animal models and in...
Published: 11/13/2023   |   Inventor(s): Thomas Angelini, Glyn Palmer, Jon Dobson, Peter McFetridge, Clayton Mathews, Brent Sumerlin, Steven Chisolm, Vignesh Subramaniam, Carolina Abrahan, Andreas Baudy, Brett Higgins
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Diagnostics
pLSC6 Predictive Scoring System for Pediatric Acute Myeloid Leukemia (AML)
Identifies Relapse Risk and Treatment Outcomes of Patients Using a Six-Gene Genetic Panel This pLSC6 predictive scoring system identifies relapse risk and treatment outcomes in acute myeloid leukemia (AML) patients based on the expression levels of six genes. The persistence of leukemic stem cells (LSC) is the primary cause of acute myeloid leukemia...
Published: 6/23/2023   |   Inventor(s): Jatinder Lamba, Abdelrahman Elsayed, Stan Pounds, Xueyuan Cao
Keywords(s):  
Category(s): Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Diagnostics
Charge-Neutral Microgels for 3D Cell Culture and Printing
Improves permeability, allowing for easier perfusion than previous compositions These charge-neutral microgels allow for 3D cell culture and printing. Bioprinting, or placement of biological samples into 3D support media, models cellular morphology, heterogeneity, and genetic profiles in a more accurate and reproducible fashion than traditional 2D...
Published: 5/17/2023   |   Inventor(s): Thomas Angelini, Brent Sumerlin, Christopher O'Bryan, Georg Scheutz
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Diagnostics
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