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A System for Prevention of Amputation in Peripheral Artery disease Patients or Diabetes patients using GenAI, Deep learning and novel viz techniques

AI-driven system predicts amputation risk with high accuracy in patients , offering personalized treatment recommendations Background: The prevention of lower extremity amputations in patients with Peripheral Artery Disease (PAD) and Diabetes Mellitus remains a critical challenge in healthcare. Current approaches lack predictive capabilities to identify...

Published: 3/31/2026 | Updated: 7/7/2025 | Inventor(s): Saeed Amal

Keywords(s):

Category(s): Technology Classifications > 3. Computer Science > AI, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Digital Health

Frogligo tRNA chaining strategy

Connecting multiple tRNA molecules, including in vitro transcribed as well as native tRNAs, to enable sequencing and structural applications Background: Transfer RNA (tRNA) molecules play a crucial role in biological processes, but technical limitations hinder their analysis. The short length of individual tRNAs makes them challenging to sequence...

Published: 5/26/2026 | Updated: 6/13/2025 | Inventor(s): Miten Jain, Stuart Akeson, Hugh Olsen, Robin AbuShumays, Nicolette Thomas, Mark Akeson

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Bioinformatics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

GlycoFix-3 (Structurally and Functionally Repaired Endothelial Glycocalyx, 3rd Edition)

GlycoFix-2 is a chemical formulation that repairs blood vessel linings to prevent heart diseasesGlycoFix-2: Chemical Repair of Blood Vessel Linings for Heart Disease PreventionBackground The endothelial glycocalyx is a sugar mesh coat that serves as a protective barrier for endothelial cells, such as blood vessels. The endothelial glycocalyx can...

Published: 5/26/2026 | Updated: 1/3/2025 | Inventor(s): Eno Ebong, Solomon Mensah, Ronodeep Mitra

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

Mitochondria transplantation in immune effector cells using droplet microfluidics and a sorter device for activating, modulating, or inhibiting immune cell activity or any cancer or tissue cell type

Search Result Description Here Copy Image URL via instructions below Copy Image URL via instructions below INV-23048 Background: Mitochondria are intracellular organelles that power cells by maintaining cellular homeostasis and contributing to vital cellular functions. They play an instrumental role in immune cell maintenance by...

Published: 7/16/2026 | Updated: 1/17/2024 | Inventor(s): Tania Konry, Judene Thomas, Agustin De Ganzó

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology

DNA-based method for rapid capture, detection and analysis of viruses on surfaces

A sensitive and rapid alternative to current viral detection methods INV-21083 Background Thousands of deaths are occurring yearly due to various viral infectious diseases, which has resulted in global public health crisis. COVID‑19 has further brought into focus, the critical need for early detection to prevent transmission, apply effective...

Published: 5/26/2026 | Updated: 1/22/2022 | Inventor(s): Sara Rouhanifard

Keywords(s): Bio-imaging, COVID-19, Diagnostic tool, virus

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Diagnostics, Technology Classifications > Life Science

Site-specific Modification of Antibody through a Tranglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan

Site-specific Modification of Antibody through a Transglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan Technical advancement of site-specific antibody engineering creating more homogenous biologics Institute Reference: INV-21035 Background Antibodies are a predominant class of macromolecules with wide-spread...

Published: 5/26/2026 | Updated: 1/10/2022 | Inventor(s): Zhaohui Zhou, Amissi Sadiki

Keywords(s): Antibody conjugates, Endoglycosidase, Glycan remodeling, Glycoengineering, Transglutaminase

A benchtop platform to rapidly produce nanofibrous materials

INV-21085 Background Nanofibrous scaffolds can mimic the mechanical and structural properties of the natural extracellular matrix (ECM) and tissues (e.g., collagenous tissues), thereby demonstrating high potential in tissue engineering and regenerative medicine. However, the rapid and reproducible fabrication of biomimetic scaffolds for tissue engineering...

Published: 5/26/2026 | Updated: 6/26/2021 | Inventor(s): Leila Deravi, Cassandra Martin, Jeffrey Paten

Keywords(s): biomaterial-based scaffold, Collagen, concentric cylinders, fibril alignment

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Not in use > -Materials

Differentiation of Olfactory Mucosa Derived Mesenchymal Stem Cells to Schwann Cells for Peripheral Nerve Repair

rder-collapse: collapse; } INV-21115 Background Peripheral nerve injuries resulting from trauma can be severe and permanently debilitating. Nerve autografting is the current gold standard for the treatment of such injuries. However, after grafting, in approximately one-third of cases, incomplete recovery with poor restoration of function is observed....

Published: 5/26/2026 | Updated: 6/26/2021 | Inventor(s): Ryan Koppes, Katelyn Neuman, Abigail Koppes, Aidan Kenny

Keywords(s): Biomedical implants, Cell Culture, Neurological Disease

Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

METHODS OF MAKING GELS AND FILMS USING CURLI NANOFIBERS

INV-21044 Background The curli system is the primary structural component of bacterial biofilm that promotes bacterial adhesion. This system is composed of highly robust amyloid nanofibers that have self-assembly properties and high resistance to harsh environmental conditions. Such unique properties make these nanofibers attractive for the production...

Published: 5/26/2026 | Updated: 6/12/2021 | Inventor(s): Neel Joshi

Keywords(s):

Category(s): Technology Classifications > 2. Physical Science > Environmental/Clean tech, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Delivery

Transwell Millifluidic

INV-19073 Background Many common microfluidic devices experience issues with cell seeding due to their small dimensions and need to be seeded using perfusion. Similarly, the diffusion of nutrients, including oxygen, is limited in many common microfluidics also due to small dimensions. Additionally, while immunofluorescence is the main analytical assay...

Published: 12/11/2025 | Updated: 12/10/2020 | Inventor(s): Eno Ebong, Ian Harding, Ira Herman, Abigail Koppes, Alex Caraballo

Keywords(s): Biotech, Cardiovascular, Devices

Category(s): Technology Classifications > 2. Physical Science > Lab tech/equipment, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Discovery, Technology Classifications > Life Science, Technology Classifications > Physical Science

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