Search Results - technology+category+%3e+therapeutics

4 Results Sort By:
“Smart” Glucose-Responsive Insulin
Technology Summary A "smart" or glucose-responsive insulin that can automatically respond to changes in a patient’s blood stream and help treat patients with type 1 diabetes. This technology comprises compositions that integrate a zwitterionic polymer, insulin moieties, saccharide moieties, and saccharide binding molecules to create...
Published: 1/9/2026   |   Updated: 1/9/2026   |   Inventor(s): Zhiqiang Cao
Keywords(s):  
Category(s): Technology Category > Biological materials, Technology Category > Chemical Processing/Synthesis, Technology Category > Drug Delivery, Technology Category > Process/Procedure, Technology Category > Small molecule, Technology Category > Therapeutics, Technology Category > Life Science
Discovery of Well Defined Sulfated Glycopolymers as Specific Heparanase Inhibitors for Cancer Therapeutics
The remodeling of the extracellular matrix has been shown to be highly upregulated in cancer and inflammation and is critically linked to the processes of invasion and metastasis. The finding that heparanase is elevated in a wide variety of tumor types and is subsequently linked to the development of pathological processes has led to an explosion of...
Published: 9/15/2025   |   Updated: 12/2/2020   |   Inventor(s): Hien Nguyen, Ravi Loka, Eric Sletten, Israel Vlodavsky
Keywords(s): Cancer, Cancer Therapies, Pharmaceuticals, Therapeutics
Category(s): Technology Category > Therapeutics, Technology Category > Pharmaceuticals, Technology Category > Oncology, Technology Category > Life Science
SH80 Combinations
BackgroundSH35/SH80 evolved from an effort to improve upon the anti-tumor activity of XK469. XK469 is a compound, currently in Phase 1 clinical trials. The clinical trials include patients with bladder, breast, colorectal, esophageal, head and neck, kidney, liver, lung, mesothelioma, pancreas and sarcoma cancers. Moving a chlorine atom from one position...
Published: 9/15/2025   |   Updated: 8/3/2017   |   Inventor(s): Lisa Polin
Keywords(s): Anti-cancer, Compound
Category(s): Technology Category > Therapeutics, Technology Category > Oncology, Technology Category > Life Science
A Diagnostic Marker for Matrix Metalloprotease (MMP)-2 and -9 Activity in Cancer Tissue
This invention is a new and simple method for the identification of active versus latent matrix metalloprotease enzymes (MMPs) in tissue. Technology Summary MMPs are involved in tumor progression and therefore are targets for anti-cancer drug therapies. However, most drug therapies directed at inhibition of MMPs have failed because there is no reliable...
Published: 6/2/2026   |   Updated: 5/6/2010   |   Inventor(s): Avraham Raz, Rafael Fridman, Pratima Nangia-Makker
Keywords(s): Biomarker, Cancer, Driving Lifelong Health, Enzyme, Method
Category(s): Technology Category > Therapeutics, Technology Category > Research tools, Technology Category > Oncology, Technology Category > Life Science, Technology Category > Diseases, Technology Category > Research tools > Antibodies