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Nucleic Acid-based Compositions and Methods for the Detection of Pathogenic Candida or Aspergillus Fungi Species
This invention pertains to the development of oligonucleotides for the rapid nucleic acid-based identification of Candida or Aspergillus fungi species in biological samples. This identification is accomplished by the targeting the internally transcribed spacer-2 (ITS2) region that are unique to various Candida species. The assay is sensitive, specific...
Published: 10/28/2024
|
Inventor(s):
Errol Reiss
,
Brian Holloway
,
Jong Shin
,
Christine Morrison
Keywords(s):
AIDS
,
Aspergilli
,
Aspergillus
,
assay
,
CANDIDA
,
CANDIDA ALBICANS
,
candidiasis
,
CDC Docket Import
,
CDC Docket Import CDC Prosecuting
,
Compositions
,
DA1XXX
,
DAXXXX
,
Detection
,
diagnostic
,
DXXXXX
,
FUNGAL
,
FUNGI
,
FUNGI COMPONENTS
,
fungus
,
HIV
,
Immuno-comprimised
,
IMMUNOCOMPROMISED
,
Methods
,
Spp
,
thrush
,
VKXXXX
,
VOXXXX
,
VPXXXX
,
WBXXXX
,
WCXXXX
,
WIXXXX
,
XCXXXX
,
XEXXXX
,
YBXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Research Materials
,
Application > Diagnostics
,
TherapeuticArea > Ophthalmology
,
TherapeuticArea > Cardiology
,
Application > Occupational Safety and Health
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Dental
,
Application > Consumer Products
,
TherapeuticArea > Oncology
,
TherapeuticArea > Endocrinology
Real-Time PCR for Detecting Legionella Species and Discriminating Legionella pneumophila
Legionella pneumophila is the causative species in most cases of Legionnaires' disease (LD). CDC scientists have developed a real-time PCR assay capable of detecting all Legionella species and discriminating L. pneumophila from other Legionella species. LD is typically difficult to diagnose from a clinical standpoint as it confers no unique clinical...
Published: 10/28/2024
|
Inventor(s):
Brian Holloway
,
Karen McCaustland
,
Patrick Yang
,
Robert Benson
Keywords(s):
DA3XXX
,
DAXXXX
,
Detection
,
DXXXXX
,
L.
,
LEGIONELLA
,
Multiplexed
,
PCR
,
Pneumophilia
,
REAL-TIME
,
Spp
Category(s):
Collaboration Sought > Licensing
,
TherapeuticArea > Infectious Disease
,
Application > Diagnostics