Search Results - richard+cross

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4(1H)-Quinolones Having Antimalarial Activity with Reduced Chemical Resistance
Competitive Advantages Potent anti-malarial activity Improved chemical resistance against multi-drug resistant (MDR) parasites Acts on both MDR parasites and drug susceptible anti-malarial strains equally well Summary This invention promises a great approach to treat those affected with malaria. The compound possesses a potent EC50...
Published: 8/27/2023   |   Inventor(s): Alexis LaCrue, Dennis Kyle, Fabian Saenz, Jordany Maignan, Niranjan Namelikonda, Richard Cross, Tina Mutka, Roman Manetsch
Keywords(s):  
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical
Compounds Having Anti-Parasitic or Anti-Infective Activity
Competitive Advantages Effective on liver and blood stages of malaria Effective against drug-resistant strains of Plasmodium parasites Summary Chloroquine replacement drugs are urgently needed to treat and prevent malaria. The endoperoxides, like artemisinin are being used in other parts of the world for malaria therapy. However, the...
Published: 8/27/2023   |   Inventor(s): Aaron Nilsen, David Hinrichs, Dennis Kyle, Jane Kelly, Jeremy Burrows, Martin Smilkstein, Michael Riscoe, Richard Cross, Rolf Winter, Roman Manetsch
Keywords(s):  
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Pharmaceuticals