Search Results - radicals

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Immunological Detection of Free Radicals In Animals and In Vitro
Electron Spin Resonance (ESR) is an universal, specific tool for the detection of free radicals in biological systems. Its application to the investigation of free radicals from whole animals, organs, and cells has been made possible by the spin-trapping technique. In a Spin-trapping experiment, a spin trap such as DMPO (5,5-dimetryl-1-pyrroline N-oxide)...
Published: 10/28/2024   |   Inventor(s): Charles Detweiler, Ronald Mason
Keywords(s): Animals, Detection, FREE, IMMUNOLOGICAL, Listed LPM Vepa as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Radicals, RXXXXX, Vitro
Category(s): Collaboration Sought > Licensing, Application > Research Materials
Mouse Monoclonal Antibody to the Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO)
Oxidative stress resulting in the formation of biological radicals has been implicated in a number of human diseases, such as cancer as well as aging. There is, however, a paucity of reliable methods for in vivo or ex vivo detection of radical formation. Until now the only general technique that allowed for the detection of these highly reactive species...
Published: 10/28/2024   |   Inventor(s): Marilyn (Estate of) Ehrenshaft, Ronald Mason
Keywords(s): 5, 5-dimethyl-1-pyrroline, AC5XXX, ACXXXX, ANTIBODY, AXXXXX, Detection, DMPO, ELISA, End-products, I cell disease, MBb, ML 2, ML 3 A, ML 4, monoclonal, Mouse, Mucolipidosis type 3 A, Mucolipidosis type 4, Nitrone, N-oxide, Protein, Radicals, RXXXXX, Sandwich, Specific, SPIN, STABLE, TRAP
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Research Materials