Search Results - polyomavirus

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T Cell-Based Adoptive Transfer Immunotherapy for Polyomavirus-Associated Pathologies
Available for licensing are methods to generate T cells responsive to multiple polyomaviruses. The resulting T cell populations could be useful in treating immunosuppressed individuals with polyomavirus infections or polyomavirus-associated pathologies such as Merkel cell carcinoma (MCC), polyomavirus-associated nephropathy (PVAN), hemorrhagic cystitis,...
Published: 10/28/2024   |   Inventor(s): Dhanalakshmi (Donna) Chinnasamy, Pawel Muranski, Christopher Buck, John Barrett
Keywords(s): adoptive transfer, BKV, CB2AXX, CB6XXX, Immunotherapy, Merkel, MKV, Patent Category - Biotechnology, Polyoma, polyomavirus, viral, virus, VLXXXX, WJXXXX, XAXXXX, XEXXXX, YAXXXX, YBXXXX
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, ResearchProducts > Antibodies, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology
Methods for Prevention and Treatment of Polyomavirus Infection or Reactivation (E-179-2007)
Available for licensing and commercial development are methods of using Tranilast [N-(3',4'-dimethoxycinnamoyl)anthranilic acid] in the prevention and treatment of human polyomavirus infection. Treatment with Tranilast decreases viral protein expression for two human polyomavirus species, JC virus (JCV) and BK virus (BKV). Furthermore, the increase...
Published: 4/8/2024   |   Inventor(s): Jeffrey Kopp, Eugene Major, Veerasamy Ravichandran
Keywords(s): BBXXXX, BK, BKV, DB4XXX, DBXXXX, DXXXXX, HIV AIDS, IMMUNOCOMPROMISED, Infection, inhibitor, JC, JCV, leukoencephalopathy, lymphoma, nephrophathy, PML, polyomavirus, Polyomavirus Infections, Polyomaviruses, Progressive multifocal leukoencephalopathy, TGF-B, Tranilast, virus
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics