Search Results - pawel+kiela

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Design and Synthesis of Pro-Drugs for Selective, Oral Delivery to the Gastrointestinal Tract
This invention provides a method for oral administration and targeted delivery of pro-drugs bonded to a carbohydrate-based molecular scaffold to the gastrointestinal tract, where the pro-drug is released directly in the gastrointestinal (GI) tract by nitroreductase enzymes naturally present. This technology provides a means of delivery of GI therapies...
Published: 3/12/2024   |   Inventor(s): Eugene Mash, Jr., Pawel Kiela
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Gastroenterology Disease
Novel 5-Fluorouracil Prodrug For Colorectal Cancer Therapy
This invention provides a method for a targeted delivery of a commonly used chemotherapy drug, 5-fluorouracil used to treat colorectal cancer. A pro-drug is released within the colon to release the active ingredient. The method will allow for targeted delivery of 5-fluorouracil to the colon. Background: Colorectal cancer is the third most commonly...
Published: 3/12/2024   |   Inventor(s): Eugene Mash, Jr., Pawel Kiela
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology